Complete Nucleotide Sequence of the First KPC-2- and SHV-12-Encoding IncX Plasmid, pKpS90, from Klebsiella pneumoniae

Najiby Kassis-Chikhani; L. Frangeul; Laurence Drieux; Christian Sengelin; Vincent Jarlier; Sylvain Brisse; Guillaume Arlet; Dominique Decré

doi:10.1128/AAC.01712-12

Journal articles

Complete Nucleotide Sequence of the First KPC-2- and SHV-12-Encoding IncX Plasmid, pKpS90, from Klebsiella pneumoniae

Najiby Kassis-Chikhani ^{1, 2} L. Frangeul ³ Laurence Drieux ^{4, 5} Christian Sengelin ^{1, 2} Vincent Jarlier ^{4, 6} Sylvain Brisse ⁷ Guillaume Arlet ^{4, 8, *} Dominique Decré ^{4, 9}

* Corresponding author

1 Hôpital Paul Brousse

2 AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP)

3 Génopole

4 Laboratoire de Bactériologie, Faculté de médecine

5 CHU Charles Foix [AP-HP]

6 CHU Pitié-Salpêtrière [AP-HP]

7 PF8 - Génotypage des Pathogènes et Santé Publique (Plate-forme)

8 Service de Bactériologie [CHU Tenon]

9 Service de microbiologie [CHU Saint-Antoine]

Abstract : We report the complete nucleotide sequence of the pKpS90 plasmid, carrying the bla KPC-2 and bla SHV-12 genes. This plasmid was isolated from a sequence type 258 (ST258) Klebsiella pneumoniae strain responsible for an outbreak in a French university hospital in 2009. pKpS90 is a 53,286-bp plasmid that belongs to the IncX incompatibility group. pKpS90 consists of a backbone from IncX plasmids, in which the KPC-2-encoding Tn 4401 transposon and a bla SHV-12 -encoding region have been inserted.

Document type :

Journal articles

Domain :

Computer Science [cs] / Bioinformatics [q-bio.QM]

Life Sciences [q-bio] / Biochemistry, Molecular Biology / Genomics [q-bio.GN]

Life Sciences [q-bio] / Microbiology and Parasitology / Virology

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https://hal-pasteur.archives-ouvertes.fr/pasteur-03252025
Contributor : Lionel Frangeul Connect in order to contact the contributor
Submitted on : Monday, June 7, 2021 - 2:52:05 PM
Last modification on : Friday, August 5, 2022 - 3:42:04 AM

Complete Nucleotide Sequence of the First KPC-2- and SHV-12-Encoding IncX Plasmid, pKpS90, from Klebsiella pneumoniae

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Complete Nucleotide Sequence of the First KPC-2- and SHV-12-Encoding IncX Plasmid, pKpS90, from Klebsiella pneumoniae

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