OP0107 HETEROZYGOUS MUTATIONS IN COPA ARE ASSOCIATED WITH ENHANCED TYPE I INTERFERON SIGNALLING

Marie-Louise Frémond (1) , Alice Lepelley (1) , Carolina Uggenti (2) , Maria José Martin-Niclos (2) , Marine Depp (3) , Vincent Bondet (3) , Darragh Duffy (3) , Gillian Rice (4) , Mary Brennan (5) , Caroline Thumerelle (6) , Siham Boulisfane (6) , Marie Legendre (7, 8) , Serge Amselem (7, 8) , Thierry Molina (9) , Nadia Nathan (10) , Yanick Crow (1, 2)

1 Imagine - U1163 - Imagine - Institut des maladies génétiques (IHU)
2 IGMM - MRC Institute of Genetics and Molecular Medicine [Edinburgh]
3 Immunobiologie des Cellules dendritiques
4 MAHSC - Manchester Academic Health Science Centre
5 Royal Hospital for Sick Children [Edinburgh]
6 CHRU Lille - Centre Hospitalier Régional Universitaire [CHU Lille]
7 CHU Trousseau [APHP]
8 SU - Sorbonne Université
9 Hôpital Necker - Enfants Malades [AP-HP]
10 RespiRare - Centre pédiatrique de pneumologie et de référence pour les maladies pulmonaires rares [AP-HP Hôpital Robert Debré]

Domaines: Sciences du Vivant [q-bio]

Marie-Louise Frémond, Alice Lepelley, Carolina Uggenti, Maria José Martin-Niclos, Marine Depp, et al.. OP0107 HETEROZYGOUS MUTATIONS IN COPA ARE ASSOCIATED WITH ENHANCED TYPE I INTERFERON SIGNALLING. Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019, Jun 2019, Madrid, Spain. pp.127.1-127, ⟨10.1136/annrheumdis-2019-eular.4158⟩. ⟨pasteur-03251879⟩