The hepatitis B virus

Pierre Tiollais (1) , Christine Pourcel (1) , Anne Dejean (1)

1 Recombinaison et Expression Génétique

DNA recombinant technology has radically changed hepatitis B virus (HBV) virology. The genetic organization, transcription and replication of the virus are basically understood, structures of integrated HBV sequences in hepatocellular carcinoma have been characterized, and new vaccines produced by recombinant DNA technique are being developed.

Domaines: Sciences du Vivant [q-bio]

Pierre Tiollais, Christine Pourcel, Anne Dejean. The hepatitis B virus. Nature, 1985, 317 (6037), pp.489-495. ⟨10.1038/317489a0⟩. ⟨pasteur-03238345⟩