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Nuclear and unclear functions of SUMO

Abstract : Post-translational modification by the ubiquitin-like SUMO protein is emerging as a defining feature of eukaryotic cells. Sumoylation has crucial roles in the regulatory challenges that face nucleate cells, including the control of nucleocytoplasmic signalling and transport and the faithful replication of a large and complex genome, as well as the regulation of gene expression.
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Jacob-Sebastian Seeler, Anne Dejean. Nuclear and unclear functions of SUMO. Nature Reviews Molecular Cell Biology, Nature Publishing Group, 2003, 4 (9), pp.690-699. ⟨10.1038/nrm1200⟩. ⟨pasteur-03237045⟩



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