Journal articles

Diversity in immunogenomics: the value and the challenge

Kerui Peng ¹ Yana Safonova ^{2, 3} Mikhail Shugay ^{4, 5} Alice B. Popejoy ⁶ Oscar L. Rodriguez ³ Felix Breden ⁷ Petter Brodin ^{8, 9} Amanda M. Burkhardt ¹ Carlos Bustamante ⁶ Van-Mai Cao-Lormeau ¹⁰ Martin M. Corcoran ⁸ Darragh Duffy ¹¹ Macarena Fuentes-Guajardo ¹² Ricardo Fujita ¹³ Victor Greiff ¹⁴ Vanessa D. Jönsson ¹⁵ Xiao Liu ¹⁶ Lluis Quintana-Murci ^{17, 18} Maura Rossetti ¹⁹ Jianming Xie ¹ Gur Yaari ²⁰ Wei Zhang ²¹ Malak S. Abedalthagafi ²² Khalid O. Adekoya ²³ Rahaman A. Ahmed ²³ Wei-Chiao Chang ^{24, 25} Clive Gray ^{26, 27} Yusuke Nakamura ²⁸ William D. Lees ²⁹ Purvesh Khatri ⁶ Houda Alachkar ¹ Cathrine Scheepers ^{30, 31} Corey T. Watson ³ Gunilla B. Karlsson Hedestam ⁸ Serghei Mangul ^{1, *}

* Corresponding author

1 USC - University of Southern California

2 UC San Diego - University of California [San Diego]

3 University of Louisville

4 RAS - Russian Academy of Sciences [Moscow]

5 Pirogov Russian National Research Medical University [Moscow, Russia]

6 Stanford University

7 SFU.ca - Simon Fraser University

8 Karolinska Institutet [Stockholm]

9 Karolinska University Hospital [Stockholm]

10 ILM - Institut Louis Malardé [Papeete]

11 Immunologie Translationnelle - Translational Immunology lab

12 Universidad de Tarapaca

13 Universidad de San Martín de Porres

14 UiO - University of Oslo

15 Beckman Research Institute [Duarte, CA]

16 Tsinghua Shenzhen International Graduate School [Shenzhen]

17 Génétique Evolutive Humaine - Human Evolutionary Genetics

18 Chaire Génomique humaine et évolution

19 UCLA - University of California [Los Angeles]

20 Bar-Ilan University [Israël]

21 CUHK - City University of Hong Kong [Hong Kong]

22 King Abdulaziz City for Science and Technology [Riyadh]

23 University of Lagos

24 Taipei Medical University

25 TMU-ShuangHo Hospital [New Taipei City]

26 University of Cape Town

27 Groote Schuur Hospital, University of Cape Town, South Africa.

28 Japanese Foundation for Cancer Research [Tokyo, Japan]

29 Birkbeck College [University of London]

30 NICD - National Institute for Communicable Diseases [Johannesburg]

31 WITS - University of the Witwatersrand [Johannesburg]

Abstract : Immunogenomics studies have been largely limited to individuals of European ancestry, restricting the ability to identify variation in human adaptive immune responses across populations. Inclusion of a greater diversity of individuals in immunogenomics studies will substantially enhance our understanding of human immunology.

Document type :

Journal articles

Domain :

Life Sciences [q-bio] / Immunology

Complete list of metadata

https://hal-pasteur.archives-ouvertes.fr/pasteur-03236474
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Submitted on : Wednesday, May 26, 2021 - 11:42:42 AM
Last modification on : Thursday, April 7, 2022 - 10:10:54 AM