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Emergence of azole resistant-Aspergillus fumigatus infections during STAT3-deficiency

Abstract : Introduction. Signal transducer and activator of transcription 3 (STAT3) deficiency is a rare primary immunodeficiency associated with increased susceptibility to bacterial and fungal infections, notably pulmonary aspergillosis. Aim. We describe the emergence of azole-resistant Aspergillus fumigatus infections in STAT3-deficient patients. Methodology. During a retrospective study of 13 pulmonary aspergillosis cases in STAT3-deficient patients conducted in France, we identified patients infected with azole-resistant A. fumigatus isolates.
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Submitted on : Monday, May 10, 2021 - 2:26:29 PM
Last modification on : Wednesday, July 21, 2021 - 4:10:02 PM

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François Danion, Amélie Duréault, Cécile Gautier, Agathe Senechal, Florence Persat, et al.. Emergence of azole resistant-Aspergillus fumigatus infections during STAT3-deficiency. Journal of Medical Microbiology, Society for General Microbiology, 2020, 69 (6), pp.844 - 849. ⟨10.1099/jmm.0.001200⟩. ⟨pasteur-03222736⟩



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