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Journal Articles Cell Year : 2019

Optimal Decoding of Cellular Identities in a Genetic Network

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Abstract

Highlights d Optimal decoding of gene expression levels can be derived from first principles d Applied to Drosophila gap genes, it specifies individual cells with 1% precision d Decoder correctly predicts downstream events in wild-type and mutant embryos d Molecular logic of gap gene readout must implement nearly optimal computations
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Dates and versions

pasteur-03216294 , version 1 (03-05-2021)

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Mariela D Petkova, Gašper Tkačik, William Bialek, Eric F Wieschaus, Thomas Gregor. Optimal Decoding of Cellular Identities in a Genetic Network. Cell, 2019, 176 (4), pp.844 - 855.e15. ⟨10.1016/j.cell.2019.01.007⟩. ⟨pasteur-03216294⟩
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