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Persistent risk of adult T-cell leukemia/lymphoma after neonatal HTLV-1 infection through exchange transfusion

Abstract : A 36-year-old Caucasian male presented with adult T-cell leukemia/lymphoma (ATL). HTLV-1 contamination was attributed to a neonatal exchange transfusion. Remission was achieved but 11 years later he presented with symptoms suggesting ATL relapse. Molecular studies of T-cell clonality and virus integration sites revealed a clonal disease, distinct from the first tumor.
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https://hal-pasteur.archives-ouvertes.fr/pasteur-03208072
Contributor : Olivier Cassar <>
Submitted on : Monday, April 26, 2021 - 12:03:26 PM
Last modification on : Friday, June 4, 2021 - 4:54:02 PM

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Eric Oksenhendler, Jocelyn Turpin, Raphael Lhote, Olivier Cassar, Jean-Michel Cayuela, et al.. Persistent risk of adult T-cell leukemia/lymphoma after neonatal HTLV-1 infection through exchange transfusion. International Journal of Hematology, Springer Verlag, 2017, 105 (6), pp.859-862. ⟨10.1007/s12185-016-2174-0⟩. ⟨pasteur-03208072⟩

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