Bordetella parapertussis Bacteremia: Clinical Expression and Bacterial Genomics

Julie Toubiana (1, 2, 3) , Saba Azarnoush (4) , Valérie Bouchez (1) , Annie Landier (1) , Sophie Guillot (1) , Soraya Matczak (2) , Stéphane Bonacorsi (5) , Sylvain Brisse (1, 3)

1 Biodiversité et Epidémiologie des Bactéries pathogènes - Biodiversity and Epidemiology of Bacterial Pathogens
2 Département de Pédiatrie et maladies infectieuses [CHU Necker]
3 CNR - Centre national de Référence de la Coqueluche et autres Bordetelloses - National Reference Center for Whooping Cough and other Bordetella infections
4 Unité d'Hémato-Immunologie pédiatrique [Hôpital Robert Debré, Paris]
5 AP-HP Hôpital universitaire Robert-Debré [Paris]

Whooping cough's primary etiological agent is Bordetella pertussis. The closely related Bordetella parapertussis rarely causes severe disease. Here we report an unusual case of bacteremia caused by B. parapertussis, review the literature, and characterize the genomic sequence of the bacterial isolate in comparison with B. parapertussis isolates from respiratory infections.

Keywords: bacteremia; Bordetella parapertussis; children; genomics

Domains: Bacteriology; Life Sciences [q-bio]

Julie Toubiana, Saba Azarnoush, Valérie Bouchez, Annie Landier, Sophie Guillot, et al.. Bordetella parapertussis Bacteremia: Clinical Expression and Bacterial Genomics. Open Forum Infectious Diseases, 2019, 6 (4), pp.ofz122. ⟨10.1093/ofid/ofz122⟩. ⟨pasteur-03206244⟩