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Is it time to reconsider initial antibiotic treatment strategies for severe urinary tract infections in Europe?

J.R. Zahar 1 M. Lecuit 1 E. Carbonnelle 1 F. Ribadeau-Dumas 1 X. Nassif 1 O. Lortholary 1, *
* Corresponding author
1 Centre d'infectiologie Necker-Pasteur [CHU Necker]
Abstract : Until recently, most reported cases of bacteraemia caused by multidrug-resistant strains of Enterobacteriacae producing an extended-spectrum b-lactamase (ESBL) in Europe have been nosocomial in origin. However, increasing numbers of reports of community-acquired bacteraemia and urinary tract infection caused by ESBL-producing microorganisms suggest that the geographical origin of patients should be taken into account as a risk-factor for possible ESBL production. Early identification of patients at highrisk of infection with ESBL-producing microorganisms, based on their geographical origin and travel history, should help to optimise initial antibiotic treatment strategies for severe urinary tract infections in Europe.
Keywords : Antibiotic therapy bacteraemia extended-spectrum b-lactamase geographical origin risk-factor urinary tract infection
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Submitted on : Wednesday, April 21, 2021 - 1:30:31 PM
Last modification on : Saturday, July 17, 2021 - 3:42:29 AM

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J.R. Zahar, M. Lecuit, E. Carbonnelle, F. Ribadeau-Dumas, X. Nassif, et al.. Is it time to reconsider initial antibiotic treatment strategies for severe urinary tract infections in Europe?. Clinical Microbiology and Infection, Elsevier for the European Society of Clinical Microbiology and Infectious Diseases, 2007, 13 (3), pp.219-221. ⟨10.1111/j.1469-0691.2007.01666.x⟩. ⟨pasteur-03204201⟩

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