A community resource for paired genomic and metabolomic data mining

Michelle A. Schorn (1) , Stefan Verhoeven (2) , Lars Ridder (2) , Florian Huber (2) , Deepa D. Acharya (3) , Alexander A. Aksenov (4) , Gajender Aleti (4) , Jamshid Amiri Moghaddam (5) , Allegra T. Aron (4) , Saefuddin Aziz (6, 7) , Anelize Bauermeister (4, 8) , Katherine D. Bauman (4) , Martin Baunach (9) , Christine Beemelmanns (5) , J. Michael Beman (10) , María Victoria Berlanga-Clavero (11) , Alex A. Blacutt (12) , Helge B. Bode (13, 14, 15) , Anne Boullie (16) , Asker Brejnrod (4) , Tim S. Bugni (3) , Alexandra Calteau (17) , Liu Cao (18) , Víctor J. Carrión (19, 20) , Raquel Castelo-Branco (21, 22) , Shaurya Chanana (3) , Alexander B. Chase (4) , Marc G. Chevrette (3) , Leticia V. Costa-Lotufo (8) , Jason M. Crawford (23, 24) , Cameron R. Currie (3) , Bart Cuypers (25, 26) , Tam Dang (27) , Tristan de Rond (4) , Alyssa M. Demko (4) , Elke Dittmann (9) , Chao Du (19) , Christopher Drozd (12) , Jean-Claude Dujardin (26) , Rachel J. Dutton (4) , Anna Edlund (28, 4) , David P. Fewer (22) , Kyo Bin Kang , Chung Sub Kim , Ki Hyun Kim , Seoung Rak Lee , Johannes Sørensen , Neha Garg , Julia M Gauglitz , Emily C Gentry , Lena Gerwick , Evgenia Glukhov , Harald Gross , Muriel Gugger (16) , Dulce G Guillén Matus , Eric J N Helfrich , Benjamin-Florian Hempel , Jae-Seoun Hur , Marianna Iorio , Paul R Jensen , Kyo Bin Kang , Leonard Kaysser , Neil L Kelleher , Chung Sub Kim , Ki Hyun Kim , Irina Koester , Gabriele M König , Tiago Leao , Seoung Rak Lee , Yi-Yuan Lee , Xuanji Li , Jessica C Little , Katherine N Maloney , Daniel Männle , Christian Martin H. , Andrew C Mcavoy , Willam W Metcalf , Hosein Mohimani , Carlos Molina-Santiago , Bradley S Moore , Michael W Mullowney , Mitchell Muskat , Louis-Félix Nothias , Ellis O’neill , Elizabeth Parkinson , Daniel Petras , Jörn Piel , Emily Pierce , Karine Pires , Raphael Reher , Diego Romero , M. Caroline Caroline Roper , Michael Rust , Hamada Saad , Carmen Saenz , Laura M Sanchez , Christian Martin (29) , Søren Johannes Sørensen , Margherita Sosio , Roderich D Süssmuth , Douglas Sweeney , Kapil Tahlan , Regan J Thomson , Nicholas J Tobias , Amaro E Trindade-Silva , Gilles P van Wezel , Mingxun Wang , Kelly C Weldon , Fan Zhang , Nadine Ziemert , Katherine R Duncan , Max Crüsemann , Simon Rogers , Pieter C Dorrestein (4) , Marnix H Medema (1) , Justin J J van Der Hooft (1)

1 WUR - Wageningen University and Research [Wageningen]
2 Netherlands eScience Center
3 University of Wisconsin-Madison
4 UC San Diego - University of California [San Diego]
5 Leibniz Institute for Natural Product Research and Infection Biology (Hans Knoell Institute)
6 Eberhard Karls Universität Tübingen = Eberhard Karls University of Tuebingen
7 Jenderal Soedirman University [Purwokerto, Indonesia]
8 USP - Universidade de São Paulo = University of São Paulo
9 University of Potsdam = Universität Potsdam
10 UC Merced - University of California [Merced]
11 Universidad de Málaga [Málaga] = University of Málaga [Málaga]
12 UC Riverside - University of California [Riverside]
13 Goethe-University Frankfurt am Main
14 Senckenberg – Leibniz Institution for Biodiversity and Earth System Research - Senckenberg Gesellschaft für Naturforschung
15 Max Planck Institute for Terrestrial Microbiology
16 Collection des Cyanobactéries
17 GENOSCOPE - Genoscope - Centre national de séquençage [Evry]
18 CMU - Carnegie Mellon University [Pittsburgh]
19 Leiden University
20 NIOO-KNAW - Netherlands Institute of Ecology
21 Universidade do Porto = University of Porto
22 Helsingin yliopisto = Helsingfors universitet = University of Helsinki
23 Yale University [New Haven]
24 YSM - Yale School of Medicine [New Haven, Connecticut]
25 UA - University of Antwerp
26 ITM - Institute of Tropical Medicine [Antwerp]
27 TU - Technische Universität Berlin
28 JCVI - J. Craig Venter Institute [La Jolla, USA]
29 Instituto de Investigaciones Científicas y Servicios de Alta Tecnología [Panama]

Genomics and metabolomics are widely used to explore specialized metabolite diversity. The Paired Omics Data Platform is a community initiative to systematically document links between metabolome and (meta)genome data, aiding identification of natural product biosynthetic origins and metabolite structures.

Domains: Life Sciences [q-bio]

Michelle A. Schorn, Stefan Verhoeven, Lars Ridder, Florian Huber, Deepa D. Acharya, et al.. A community resource for paired genomic and metabolomic data mining. Nature Chemical Biology, 2021, ⟨10.1038/s41589-020-00724-z⟩. ⟨pasteur-03153704⟩