Bacterial Metabolism under FHA Control

Marco Bellinzoni (1) , Pedro M. Alzari (1)

1 Biochimie Structurale

The NMR structures of Corynebacterium glutamicum OdhI described by Barthe et al. in this issue of Structure reveal a major conformational rearrangement upon phosphorylation, suggesting an autoinhibition mechanism that accounts for the functional properties of the protein as a regulatory switch in glutamate metabolism.

Domains: Chemical Sciences; Cristallography; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Structural Biology [q-bio.BM]; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Computer Science [cs]; Bioinformatics [q-bio.QM]; Physics [physics]; Physics [physics]; Biological Physics [physics.bio-ph]; Life Sciences [q-bio]; Cellular Biology

Marco Bellinzoni, Pedro M. Alzari. Bacterial Metabolism under FHA Control. Structure, 2009, 17 (4), pp.487-488. ⟨10.1016/j.str.2009.03.004⟩. ⟨pasteur-03139144⟩