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Article Dans Une Revue Journal of Molecular Biology Année : 1986

Preliminary crystallographic study of the Fab fragment of a monoclonal antibody directed against a cobra cardiotoxin

Résumé

We report on the preparation, crystallization and preliminary X-ray crystallographic study of the Fab fragments from a murine monoclonal anti-cardiotoxin antibody M gamma 2-3 directed against a cobra cardiotoxin. The Fab fragment has been crystallized from polyethylene glycol 8000 solutions in a form suitable for high-resolution, X-ray crystallographic studies. The crystals are monoclinic, space group C2, with a = 161.2 A, b = 40.4 A, c = 96.5 A, beta = 118.3 degrees.

Dates et versions

pasteur-03136410 , version 1 (09-02-2021)

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Véronique Guillon, Pedro M Alzari, Jean-Marc Grognet. Preliminary crystallographic study of the Fab fragment of a monoclonal antibody directed against a cobra cardiotoxin. Journal of Molecular Biology, 1986, 189 (4), pp.723-724. ⟨10.1016/0022-2836(86)90503-6⟩. ⟨pasteur-03136410⟩

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