Abstract : Ageing is a multi-factorial condition that results in a gradual decline in tissue and organ function. Systemic, local and intrinsic factors play major roles in this process that also results in a decline in stem cell number and function. In this issue of The EMBO Journal, Li et al (2019) show that a subpopulation of mouse muscle stem cells is depleted in aged mice through loss of niche-derived granulocyte colony-stimulating factor (G-CSF).
https://hal-pasteur.archives-ouvertes.fr/pasteur-03105578 Contributor : Brendan EvanoConnect in order to contact the contributor Submitted on : Monday, January 11, 2021 - 10:48:56 AM Last modification on : Thursday, April 7, 2022 - 10:10:44 AM