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Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring

Abstract : Establishment of a fungal infection due to Aspergillus fumigatus relies on the efficient germination of the airborne conidia once they penetrate the respiratory tract. However, the features of conidial germination have been poorly explored and understood in this fungal species as well as in other species of filamentous fungi. We show here that the germination of A. fumigatus is asynchronous. If the nutritional environment and extensive gene deletions can modify the germination parameters for A. fumigatus, the asynchrony is maintained in all germinative conditions tested. Even though the causes for this asynchrony of conidial germination remain unknown, asynchrony is essential for the completion of the biological cycle of this filamentous fungus.
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https://hal-pasteur.archives-ouvertes.fr/pasteur-03105294
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Submitted on : Monday, January 11, 2021 - 8:22:44 AM
Last modification on : Thursday, May 27, 2021 - 5:08:05 PM
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François Danion, Norman van Rhijn, Alexandre Dufour, Rachel Legendre, Odile Sismeiro, et al.. Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring. Journal of Fungi, MDPI, 2021, 7 (1), pp.E30. ⟨10.3390/jof7010030⟩. ⟨pasteur-03105294⟩

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