Maternal-neonatal listeriosis

Caroline Charlier (1, 2, 3, 4) , Olivier Disson (1) , Marc Lecuit (1, 2, 3, 4)

1 Biologie des Infections - Biology of Infection
2 CNRL - Centre National de Référence Listeria - National Reference Center Listeria
3 CC-OMS / WHO-CC - Centre collaborateur de l'OMS Listeria / WHO Collaborating Centre Listeria
4 Service des Maladies infectieuses et tropicales [CHU Necker]

Listeriosis is a rare and severe foodborne infection caused by Listeria monocytogenes. It manifests as septicemia, neurolisteriosis, and maternal-fetal infection. In pregnancy, it may cause maternal fever, premature delivery, fetal loss, neonatal systemic and central nervous system infections. Maternal listeriosis is mostly reported during the 2nd and 3rd trimester of pregnancy, as sporadic cases or in the context of outbreaks. Strains belonging to clonal complexes 1, 4 and 6, referred to as hypervirulent, are the most associated to maternal-neonatal infections. Here we review the clinical, pathophysiological, and microbiological features of maternal-neonatal listeriosis.

Mots clés: listeriosis; Listeria monocytogenes; placenta; pregnancy; newborn; fetus; infection

Domaines: Sciences du Vivant [q-bio]; Médecine humaine et pathologie; Maladies infectieuses

Caroline Charlier, Olivier Disson, Marc Lecuit. Maternal-neonatal listeriosis. Virulence, 2020, 11 (1), pp.391-397. ⟨10.1080/21505594.2020.1759287⟩. ⟨pasteur-02979609⟩