Neurons Are the Inflammatory Problem, Cell, vol.173, pp.1066-1068, 2018. ,
Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin, Nature, vol.405, pp.458-462, 2000. ,
Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans, Br J Pharmacol, vol.154, pp.1558-1571, 2008. ,
Choline acetyltransferase-expressing T cells are required to control chronic viral infection, Science, vol.363, pp.639-644, 2019. ,
Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation, Nature, vol.421, pp.384-388, 2003. ,
Convergence of alpha 7 nicotinic acetylcholine receptor-activated pathways for anti-apoptosis and anti-inflammation: central role for JAK2 activation of STAT3 and NF-kappaB, Brain Res, vol.1256, pp.1-7, 2009. ,
Genomic organization and partial duplication of the human alpha7 neuronal nicotinic acetylcholine receptor gene Accepted Article This article is protected by copyright. All rights reserved (CHRNA7), Genomics, vol.52, pp.173-185, 1998. ,
A Human-Specific ?7-Nicotinic Acetylcholine Receptor Gene in Human Leukocytes: Identification, Regulation and the Consequences of CHRFAM7A Expression, Mol Med, vol.21, pp.323-336, 2015. ,
Uniquely human CHRFAM7A gene increases the hematopoietic stem cell reservoir in mice and amplifies their inflammatory response, Proc Natl Acad Sci, vol.116, pp.7932-7940, 2019. ,
Nicotine Attenuates Osteoarthritis Pain and Matrix Metalloproteinase-9 Expression via the ?7 Nicotinic Acetylcholine Receptor, J Immunol, 2019. ,
Activation of ?7 nicotinic acetylcholine receptors prevents monosodium iodoacetate-induced osteoarthritis in rats, Cell Physiol Biochem, vol.35, pp.627-638, 2015. ,
What is the effect of nicotinic acetylcholine receptor stimulation on osteoarthritis in a rodent animal model, SAGE Open Med, vol.4, p.2050312116637529, 2016. ,
Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents, J Neurosci, vol.17, pp.9165-9171, 1997. ,
Osteoarthritis development in novel experimental mouse models induced by knee joint instability, Osteoarthr Cartil, vol.13, pp.632-641, 2005. ,
Osteoprotegerin inhibits cartilage degradation through an effect on trabecular bone in murine experimental osteoarthritis, Arthritis Rheum, vol.58, pp.2379-2386, 2008. ,
The OARSI histopathology initiative -recommendations for histological assessments of osteoarthritis in the mouse ,
, Osteoarthr Cartil, vol.18, issue.3, pp.17-23, 2010.
Depletion of protease-activated receptor 2 but not protease-activated receptor 1 may confer protection against osteoarthritis in mice through extracartilaginous mechanisms, Arthritis & Rheumatology, vol.66, pp.3337-3348, 2014. ,
Accepted Article This article is protected by copyright. All rights reserved 18, Nat Protoc, vol.3, pp.1253-1260, 2008. ,
Impairment of glyoxalase-1, an advanced glycation end-product detoxifying enzyme, induced by inflammation in age-related osteoarthritis, Arthritis Res Ther, vol.21, p.18, 2019. ,
URL : https://hal.archives-ouvertes.fr/hal-01980125
Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes, Mol Pharmacol, vol.72, pp.715-724, 2007. ,
Physiological functions of the cholinergic system in immune cells, J Pharmacol Sci, vol.134, pp.1-21, 2017. ,
Role of the autonomic nervous system in osteoarthritis, Best Pract Res Clin Rheumatol, vol.31, pp.661-675, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-02180187
,
, Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit, Science, vol.334, pp.98-101, 2011.
Neurostimulation of the cholinergic anti-inflammatory pathway ameliorates disease in rat collagen-induced arthritis, PLoS ONE, vol.9, p.104530, 2014. ,
Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis ,
, Proc Natl Acad Sci, vol.113, pp.8284-8289, 2016.
Expression of the non-neuronal cholinergic system in human knee synovial tissue from patients with rheumatoid arthritis and osteoarthritis, Life Sci, vol.91, pp.1048-1052, 2012. ,
Unexpected finding of a marked non-neuronal cholinergic system in human knee joint synovial tissue, Neurosci Lett, vol.442, pp.128-133, 2008. ,
Expression of choline and acetylcholine transporters in synovial tissue and cartilage of patients with rheumatoid arthritis and osteoarthritis, Cell and Tissue Research, vol.359, p.465, 2015. ,
Functional role of acetylcholine and the expression of cholinergic receptors and components in osteoblasts. FEBS Accepted Article This article is protected by copyright, All rights reserved Lett, vol.584, pp.817-824, 2010. ,
The synthesis of acetylcholine in skeletal muscles of the rat, J Physiol (Lond), vol.322, pp.53-69, 1982. ,
Mammalian nicotinic acetylcholine receptors: from structure to function, Physiol Rev, vol.89, pp.73-120, 2009. ,
The alpha-bungarotoxin-binding nicotinic acetylcholine receptor from rat brain contains only the alpha7 subunit, J Biol Chem, vol.272, pp.24024-24029, 1997. ,
Nicotine acts on growth plate chondrocytes to delay skeletal growth through the alpha7 neuronal nicotinic acetylcholine receptor, PLoS ONE, vol.3, p.3945, 2008. ,
Janus kinase 2, an early target of alpha 7 nicotinic acetylcholine receptor-mediated neuroprotection against Abeta-(1-42) amyloid, J Biol Chem, vol.277, pp.44920-44924, 2002. ,
The selective alpha7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain slices and restores auditory gating deficits in anesthetized rats, J Pharmacol Exp Ther, vol.312, pp.1213-1222, 2005. ,
Smoking and osteoarthritis: differential effect of nicotine on human chondrocyte glycosaminoglycan and collagen synthesis, Osteoarthr Cartil, vol.13, pp.942-943, 2005. ,
CHRFAM7A alters binding to the neuronal alpha-7 nicotinic acetylcholine receptor, Neurosci Lett, vol.690, pp.126-131, 2019. ,
Up-regulation of the humanspecific CHRFAM7A gene in inflammatory bowel disease, BBA Clin, vol.5, pp.66-71, 2016. ,
Association between smoking and risk of knee osteoarthritis: a systematic review and meta-analysis, Osteoarthr Cartil, vol.25, pp.809-816, 2017. ,
Chrna7 deficient mice manifest no consistent neuropsychiatric and behavioral phenotypes, Sci Rep, vol.7, p.39941, 2017. ,
Evaluating the suitability of nicotinic acetylcholine receptor antibodies for standard immunodetection procedures, J Neurochem, vol.102, pp.479-492, 2007. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00161322
, Accepted Article