F. Agerer, S. Lux, A. Michel, M. Rohde, K. Ohlsen et al., Cellular invasion by Staphylococcus aureus reveals a functional link between focal adhesion kinase and cortactin in integrin-mediated internalisation, J Cell Sci, vol.118, pp.2189-2200, 2005.

A. I. Bakardjiev, B. A. Stacy, and D. A. Portnoy, Growth of Listeria monocytogenes in the guinea pig placenta and role of cell-to-cell spread in fetal infection, J Infect Dis, vol.191, pp.1889-1897, 2005.

H. Bierne, C. Sabet, N. Personnic, and P. Cossart, Internalins: A complex family of leucine-rich repeat-containing proteins in Listeria monocytogenes, Microbes Infect, vol.9, pp.1156-1166, 2007.
URL : https://hal.archives-ouvertes.fr/hal-02666058

M. Bonazzi and P. Cossart, Bacterial entry into cells: A role for the endocytic machinery, FEBS Lett, vol.580, pp.2962-2967, 2006.
URL : https://hal.archives-ouvertes.fr/hal-02659637

M. Bonazzi, M. Lecuit, and P. Cossart, Listeria monocytogenes internalin and E-cadherin: From structure to pathogenesis, Cell Microbiol, vol.11, pp.693-702, 2009.

M. Bonazzi, E. Veiga, J. Pizarro-cerda, and P. Cossart, Successive post-translational modifications of E-cadherin are required for InlA-mediated internalization of Listeria monocytogenes, Cell Microbiol, vol.10, pp.2208-2222, 2008.
URL : https://hal.archives-ouvertes.fr/hal-02657652

E. C. Boyle and B. B. Finlay, Bacterial pathogenesis: Exploiting cellular adherence, Curr Opin Cell Biol, vol.15, pp.633-639, 2003.

F. H. Brembeck, T. Schwarz-romond, J. Bakkers, S. Wilhelm, M. Hammerschmidt et al., Essential role of BCL9-2 in the switch between b-catenin's adhesive and transcriptional functions, Genes Dev, vol.18, pp.2225-2230, 2004.

D. H. Campbell, R. L. Sutherland, and R. J. Daly, Signaling pathways and structural domains required for phosphorylation of EMS1/cortactin, Cancer Res, vol.59, pp.5376-5385, 1999.

M. Cavey, M. Rauzi, P. F. Lenne, and T. Lecuit, A two-tiered mechanism for stabilization and immobilization of E-cadherin, Nature, vol.453, pp.751-756, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00428936

P. Cossart and P. J. Sansonetti, Bacterial invasion: The paradigms of enteroinvasive pathogens, Science, vol.304, pp.242-248, 2004.
URL : https://hal.archives-ouvertes.fr/hal-02683278

E. Delva, D. K. Tucker, and A. P. Kowalczyk, The desmosome, Cold Spring Harb Perspect Biol, vol.1, p.2543, 2009.

O. Disson, S. Grayo, E. Huillet, G. Nikitas, F. Langa-vives et al., Conjugated action of two speciesspecific invasion proteins for fetoplacental listeriosis, Nature, vol.455, pp.1114-1118, 2008.
URL : https://hal.archives-ouvertes.fr/pasteur-02456680

F. Drees, S. Pokutta, S. Yamada, W. J. Nelson, and W. I. Weis, a-catenin is a molecular switch that binds E-cadherinb-catenin and regulates actin-filament assembly, Cell, vol.123, pp.903-915, 2005.

T. Dubois, O. Paleotti, A. A. Mironov, V. Fraisier, T. E. Stradal et al., Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics, Nat Cell Biol, vol.7, pp.353-364, 2005.

S. Dupre-crochet, A. Figueroa, C. Hogan, E. C. Ferber, C. U. Bialucha et al., Casein kinase 1 is a novel negative regulator of E-cadherin-based cell-cell contacts, Mol Cell Biol, vol.27, pp.3804-3816, 2007.
URL : https://hal.archives-ouvertes.fr/inserm-00275884

Y. Fujita, G. Krause, M. Scheffner, D. Zechner, H. E. Leddy et al., Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex, Nat Cell Biol, vol.4, pp.222-231, 2002.

, Listeria monocytogenes Internalin and E-cadherin: From Bench to Bedside Cite this article as, Cold Spring Harb Perspect Biol, vol.1, p.3087, 2009.

J. L. Gaillard, P. Berche, C. Frehel, E. Gouin, and P. Cossart, Entry of L. monocytogenes into cells is mediated by internalin, a repeat protein reminiscent of surface antigens from gram-positive cocci, Cell, vol.65, pp.1127-1141, 1991.

J. L. Gaillard, P. Berche, J. Mounier, S. Richard, and P. Sansonetti, In vitro model of penetration and intracellular growth of Listeria monocytogenes in the human enterocyte-like cell line Caco-2, Infect Immun, vol.55, pp.2822-2829, 1987.

C. J. Gottardi and B. M. Gumbiner, Distinct molecular forms of b-catenin are targeted to adhesive or transcriptional complexes, J Cell Biol, vol.167, pp.339-349, 2004.

E. Gouin, M. D. Welch, and P. Cossart, Actin-based motility of intracellular pathogens, Curr Opin Microbiol, vol.8, pp.35-45, 2005.
URL : https://hal.archives-ouvertes.fr/hal-02683106

K. J. Green and C. A. Gaudry, Are desmosomes more than tethers for intermediate filaments?, Nat Rev Mol Cell Biol, vol.1, pp.208-216, 2000.

M. Hamon, H. Bierne, and P. Cossart, Listeria monocytogenes: A multifaceted model, Nat Rev Microbiol, vol.4, pp.423-434, 2006.
URL : https://hal.archives-ouvertes.fr/hal-02667803

C. R. Hauck, F. Agerer, P. Muenzner, and T. Schmitter, Cellular adhesion molecules as targets for bacterial infection, Eur J Cell Biol, vol.85, pp.235-242, 2006.

J. Heuberger and W. Birchmeier, Interplay of cadherinmediated cell adhesion and canonical Wnt signaling, Cold Spring Harb Perspect Biol, vol.2, p.2915, 2009.

C. Huang, J. Liu, C. C. Haudenschild, and X. Zhan, The role of tyrosine phosphorylation of cortactin in the locomotion of endothelial cells, J Biol Chem, vol.273, pp.25770-25776, 1998.

C. Huang, Y. Ni, T. Wang, Y. Gao, C. C. Haudenschild et al., Down-regulation of the filamentous actin crosslinking activity of cortactin by Src-mediated tyrosine phosphorylation, J Biol Chem, vol.272, pp.13911-13915, 1997.

R. R. Isberg and P. Barnes, Subversion of integrins by enteropathogenic Yersinia, J Cell Sci, vol.114, pp.21-28, 2001.

C. Jacquet, M. Doumith, J. I. Gordon, P. M. Martin, P. Cossart et al., A molecular marker for evaluating the pathogenic potential of foodborne Listeria monocytogenes, J Infect Dis, vol.189, pp.2094-2100, 2004.
URL : https://hal.archives-ouvertes.fr/hal-02683027

J. Johansson, P. Mandin, A. Renzoni, C. Chiaruttini, M. Springer et al., An RNA thermosensor controls expression of virulence genes in Listeria monocytogenes, Cell, vol.110, pp.551-561, 2002.

R. Jonquieres, H. Bierne, J. Mengaud, and P. Cossart, The inlA gene of Listeria monocytogenes LO28 harbors a nonsense mutation resulting in release of internalin, Infect Immun, vol.66, pp.3420-3422, 1998.
URL : https://hal.archives-ouvertes.fr/hal-02692385

B. Joshi, S. S. Strugnell, J. G. Goetz, L. D. Kojic, M. E. Cox et al., Phosphorylated caveolin-1 regulates Rho/ROCKdependent focal adhesion dynamics and tumor cell migration and invasion, Cancer Res, vol.68, pp.8210-8220, 2008.

P. I. Karecla, S. J. Green, S. J. Bowden, J. Coadwell, and P. J. Kilshaw, Identification of a binding site for integrin aEb7 in the N-terminal domain of E-cadherin, J Biol Chem, vol.271, pp.30909-30915, 1996.

N. Khelef, M. Lecuit, H. Bierne, and P. Cossart, Species specificity of the Listeria monocytogenes InlB protein, Cell Microbiol, vol.8, pp.457-470, 2006.

B. Kobe and J. Deisenhofer, The leucine-rich repeat: A versatile binding motif, Trends Biochem Sci, vol.19, pp.415-421, 1994.

N. Kohmura, K. Senzaki, S. Hamada, N. Kai, R. Yasuda et al., Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex, Neuron, vol.20, pp.1137-1151, 1998.

M. Lecuit, Human listeriosis and animal models, Microbes Infect, vol.9, pp.1216-1225, 2007.
URL : https://hal.archives-ouvertes.fr/hal-02666603

M. Lecuit, S. Dramsi, C. Gottardi, M. Fedor-chaiken, B. Gumbiner et al., A single amino acid in E-cadherin responsible for host specificity towards the human pathogen Listeria monocytogenes, Embo J, vol.18, pp.3956-3963, 1999.
URL : https://hal.archives-ouvertes.fr/pasteur-02456831

M. Lecuit, R. Hurme, J. Pizarro-cerda, H. Ohayon, B. Geiger et al., A role for a-and b-catenins in bacterial uptake, Proc Natl Acad Sci, vol.97, pp.10008-10013, 2000.

M. Lecuit, D. M. Nelson, S. D. Smith, H. Khun, M. Huerre et al., Targeting and crossing of the human maternofetal barrier by Listeria monocytogenes: Role of internalin interaction with trophoblast E-cadherin, Proc Natl Acad Sci, vol.101, pp.6152-6157, 2004.
URL : https://hal.archives-ouvertes.fr/pasteur-02456710

M. Lecuit, H. Ohayon, L. Braun, J. Mengaud, and P. Cossart, Internalin of Listeria monocytogenes with an intact leucine-rich repeat region is sufficient to promote internalization, Infect Immun, vol.65, pp.5309-5319, 1997.

M. Lecuit, S. Vandormael-pournin, J. Lefort, M. Huerre, P. Gounon et al., A transgenic model for listeriosis: Role of internalin in crossing the intestinal barrier, Science, vol.292, pp.1722-1725, 2001.
URL : https://hal.archives-ouvertes.fr/pasteur-02456808

N. Martinez-quiles, H. Y. Ho, M. W. Kirschner, N. Ramesh, and R. S. Geha, Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP, Mol Cell Biol, vol.24, pp.5269-5280, 2004.

P. D. Mccrea, D. Gu, and M. Balda, Junctional music that the nucleus hears, Cold Spring Harb Perspect Biol, vol.1, p.2923, 2009.

W. Meng and M. Takeichi, Adherens junction: Molecular architecture and regulation, Cold Spring Harb Perspect Biol, vol.1, p.2899, 2009.

J. Mengaud, H. Ohayon, and P. Gounon, E-cadherin is the receptor for internalin, a surface protein required for entry of L. monocytogenes into epithelial cells, Cell, vol.84, pp.923-932, 1996.

M. Ozawa, M. Ringwald, and R. Kemler, Uvomorulincatenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule, Proc Natl Acad Sci, vol.87, pp.4246-4250, 1990.

S. D. Patel, C. P. Chen, F. Bahna, B. Honig, and L. Shapiro, Cadherin-mediated cell-cell adhesion: Sticking together as a family, Curr Opin Struct Biol, vol.13, pp.690-698, 2003.

Q. T. Phan, R. A. Fratti, N. V. Prasadarao, J. E. Edwards, and S. G. Filler, N-cadherin mediates endocytosis of Candida albicans by endothelial cells, J Biol Chem, vol.280, pp.10455-10461, 2005.

Q. T. Phan, C. L. Myers, Y. Fu, D. C. Sheppard, M. R. Yeaman et al., Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells, PLoS Biol, vol.5, p.64, 2007.

J. Pizarro-cerda and P. Cossart, Bacterial adhesion and entry into host cells, Cell, vol.124, pp.715-727, 2006.

J. Pizarro-cerda, R. Jonquieres, E. Gouin, J. Vandekerckhove, J. Garin et al., Distinct protein patterns associated with Listeria monocytogenes InlA-or InlBphagosomes, Cell Microbiol, vol.4, pp.101-115, 2002.

B. Ranscht and M. T. Dours-zimmermann, T-cadherin, a novel cadherin cell adhesion molecule in the nervous system lacks the conserved cytoplasmic region, Neuron, vol.7, pp.391-402, 1991.

A. B. Reynolds, p120-catenin: Past and present, Biochim Biophys Acta, vol.1773, pp.2-7, 2007.

J. Rhee, T. Buchan, L. Zukerberg, J. Lilien, and J. Balsamo, Cables links Robo-bound Abl kinase to N-cadherinbound b-catenin to mediate Slit-induced modulation of adhesion and transcription, Nat Cell Biol, vol.9, pp.883-892, 2007.

S. Roura, S. Miravet, J. Piedra, G. De-herreros, A. Dunach et al., Regulation of E-cadherin/Catenin association by tyrosine phosphorylation, J Biol Chem, vol.274, pp.36734-36740, 1999.

W. D. Schubert, C. Urbanke, T. Ziehm, V. Beier, M. P. Machner et al., Structure of internalin, a major invasion protein of Listeria monocytogenes, in complex with its human receptor E-cadherin, Cell, vol.111, pp.825-836, 2002.

L. Shapiro and W. I. Weis, Structure and biochemistry of cadherins and catenins, Cold Spring Harb Perspect Biol, vol.1, p.3053, 2009.

S. Sousa, D. Cabanes, C. Archambaud, F. Colland, E. Lemichez et al., ARHGAP10 is necessary for a-catenin recruitment at adherens junctions and for Listeria invasion, Nat Cell Biol, vol.7, pp.954-960, 2005.

S. Sousa, D. Cabanes, L. Bougneres, M. Lecuit, P. Sansonetti et al., Src, cortactin and Arp2/3 complex are required for E-cadherin-mediated internalization of Listeria into cells, Cell Microbiol, vol.9, pp.2629-2643, 2007.
URL : https://hal.archives-ouvertes.fr/hal-02657622

S. Sousa, D. Cabanes, A. El-amraoui, C. Petit, M. Lecuit et al., Unconventional myosin VIIa and vezatin, two proteins crucial for Listeria entry into epithelial cells, J Cell Sci, vol.117, pp.2121-2130, 2004.
URL : https://hal.archives-ouvertes.fr/hal-02676456

S. Troyanovsky, Cadherin dimers in cell-cell adhesion, Eur J Cell Biol, vol.84, pp.225-233, 2005.

V. Vasioukhin and E. Fuchs, Actin dynamics and cell-cell adhesion in epithelia, Curr Opin Cell Biol, vol.13, pp.76-84, 2001.

E. Veiga and P. Cossart, Ubiquitination of intracellular bacteria: A new bacteria sensing system?, Trends Cell Biol, vol.15, pp.2-5, 2005.
URL : https://hal.archives-ouvertes.fr/hal-02678643

E. Veiga and P. Cossart, Listeria hijacks the clathrindependent endocytic machinery to invade mammalian cells, Nat Cell Biol, vol.7, pp.894-900, 2005.
URL : https://hal.archives-ouvertes.fr/hal-02683019

E. Veiga, J. A. Guttman, M. Bonazzi, E. Boucrot, A. Toledo-arana et al., Invasive and adherent bacterial pathogens co-opt host clathrin for infection, Cell Host Microbe, vol.2, pp.340-351, 2007.
URL : https://hal.archives-ouvertes.fr/hal-02658842

D. Vestweber, M. Winderlich, G. Cagna, and A. F. Nottebaum, Cell adhesion dynamics at endothelial junctions: VE-cadherin as a major player, Trends Cell Biol, vol.19, pp.8-15, 2009.

S. A. Weed, Y. Du, and J. T. Parsons, Translocation of cortactin to the cell periphery is mediated by the small GTPase Rac1, J Cell Sci, vol.111, pp.2433-2443, 1998.

M. D. Welch, J. Rosenblatt, J. Skoble, D. A. Portnoy, and T. J. Mitchison, Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleation, Science, vol.281, pp.105-108, 1998.

A. Wilde, E. C. Beattie, L. Lem, D. A. Riethof, S. H. Liu et al., EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake, Cell, vol.96, pp.677-687, 1999.

T. Wollert, D. W. Heinz, and W. D. Schubert, Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin, Proc Natl Acad Sci, vol.104, pp.13960-13965, 2007.

T. Wollert, B. Pasche, M. Rochon, S. Deppenmeier, J. Van-den-heuvel et al., Extending the host range of Listeria monocytogenes by rational protein design, Cell, vol.129, pp.891-902, 2007.

S. Wu, K. C. Lim, J. Huang, R. F. Saidi, and C. L. Sears, Bacteroides fragilis enterotoxin cleaves the zonula adherens protein, E-cadherin, Proc Natl Acad Sci, vol.95, pp.14979-14984, 1998.

S. Yamada, S. Pokutta, F. Drees, W. I. Weis, and W. J. Nelson, Deconstructing the cadherin-catenin-actin complex, Cell, vol.123, pp.889-901, 2005.

G. Zeng, U. Apte, A. Micsenyi, A. Bell, and S. P. Monga, Tyrosine residues 654 and 670 in b-catenin are crucial in regulation of Met-b-catenin interactions, Exp Cell Res, vol.312, pp.3620-3630, 2006.

, Listeria monocytogenes Internalin and E-cadherin: From Bench to Bedside Cite this article as, Cold Spring Harb Perspect Biol, vol.1, p.3087, 2009.