Case Report of Exposure to Voriconazole in the Second and Third Trimesters of Pregnancy

M Shoai Tehrani (1, 2, 3, 4) , F. Sicre de Fontbrune (5, 2) , P. Roth (2) , C. Allisy (6) , M.-E Bougnoux (4, 2) , O. Hermine (4, 2) , M. Lecuit (1, 2, 3, 7) , O. Lortholary (4, 2) , C. Charlier (1, 2, 3, 7)

1 UPD5 - Université Paris Descartes - Paris 5
2 CHU Necker - Enfants Malades [AP-HP]
3 Service des Maladies infectieuses et tropicales [CHU Necker]
4 Centre d'infectiologie Necker-Pasteur [CHU Necker]
5 IMAGINE - U1163 - Imagine - Institut des maladies génétiques
6 Centre Hospitalier Victor Dupouy
7 IP - Institut Pasteur [Paris]

Azoles, such as voriconazole, are contraindicated during pregnancy because of fetal toxicity. We report the case of a pregnant woman with invasive aspergillosis who received voriconazole without a maternofetal adverse effect [...]

Domains: Life Sciences [q-bio]; Human health and pathology; Infectious diseases; Microbiology and Parasitology; Mycology

M Shoai Tehrani, F. Sicre de Fontbrune, P. Roth, C. Allisy, M.-E Bougnoux, et al.. Case Report of Exposure to Voriconazole in the Second and Third Trimesters of Pregnancy. Antimicrobial Agents and Chemotherapy, 2013, 57 (2), pp.1094-1095. ⟨10.1128/AAC.00899-12⟩. ⟨pasteur-02924795⟩