Youth Comes But Once in a Lifetime for Adult-Born Neurons

Kurt A Sailor (1) , Pierre-Marie Lledo (1)

1 Perception et Mémoire / Perception and Memory

Using new methods to functionally dissect circuits, two papers from 2015 found enhanced synaptic properties of the inputs and outputs of hippocampal adult-born neurons specifically during a critical period of their development. These studies provided a circuit-level view of unique roles for new neurons and how they cope with the ever-changing environment.

Keywords: critical period; enriched environment; feedback inhibition; hippocampal adult neurogenesis; plasticity

Domains: Neuroscience

Kurt A Sailor, Pierre-Marie Lledo. Youth Comes But Once in a Lifetime for Adult-Born Neurons. Trends in Neurosciences, 2018, 41 (9), pp.563-566. ⟨10.1016/j.tins.2018.07.003⟩. ⟨pasteur-02887351⟩