Who Defends the Stem Cell’s Citadel?

Helene Strick-Marchand (1) , David Durantel (2)

1 Immunité Innée - Innate Immunity
2 UNICANCER/CRCL - Centre de Recherche en Cancérologie de Lyon

Recently in Cell, Wu et al. (2018) demonstrated that intrinsic expression of a subset of interferon stimulated genes confers resistance to viral infections in stem cells both in vitro and in vivo, while differentiated cells lose this intrinsic gatekeeper expression pattern in favor of inducible interferon responses.

Domaines: Immunité innée

Helene Strick-Marchand, David Durantel. Who Defends the Stem Cell’s Citadel?. Cell Stem Cell, 2018, 22 (3), pp.287-289. ⟨10.1016/j.stem.2018.02.007⟩. ⟨pasteur-02875574⟩