Assay for Hepatitis B Core-related Antigen Identify Patients With High Viral Load: Systematic Review and Meta-analysis of Individual Participant Data
Kyoko Yoshida
(1)
,
Alice Desbiolles
(2)
,
Sarah Feldman
(2)
,
Sang Hoon Ahn
(3)
,
Enagnon Alidjinou
(4)
,
Masanori Atsukawa
(5)
,
Laurence Bocket
(6)
,
Maurizia Brunetto
(7)
,
Maria Buti
(8)
,
Ivana Carey
(9)
,
Gian Paolo Caviglia
(10)
,
En-Qiang Chen
(11)
,
Markus Cornberg
(12)
,
Masaru Enomoto
(13)
,
Masao Honda
(14)
,
Christoph Höner zu Siederdissen
(12)
,
Masatoshi Ishigami
(15)
,
Harry La Janssen
(16)
,
Benjamin Maasoumy
(12)
,
Takeshi Matsui
,
Akihiro Matsumoto
(17)
,
Shuhei Nishiguchi
(18)
,
Mar Riveiro-Barciela
(8)
,
Akinobu Takaki
(19)
,
Pisit Tangkijvanich
(20)
,
Hidenori Toyoda
,
Margo Jh van Campenhout
(21)
,
Bo Wang
(9)
,
Lai Wei
(22)
,
Hwai-I Yang
(23)
,
Yoshihiko Yano
(24)
,
Hiroshi Yatsuhashi
,
Man-Fung Yuen
(25)
,
Eiji Tanaka
(17)
,
Maud Lemoine
(1)
,
Yasuhito Tanaka
(26)
,
Yusuke Shimakawa
(2)
1
Imperial College London
2 Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology
3 Yonsei University
4 Pôle de Biologie Pathologie Génétique [CHU Lille]
5 Chiba University Hospital
6 Laboratoire de virologie [CHU Lille]
7 Azienda Ospedaliera Universitaria Pisana
8 UAB - Universitat Autònoma de Barcelona
9 KCH - King's College Hospital
10 UNITO - Università degli studi di Torino = University of Turin
11 SCU - Sichuan University [Chengdu]
12 MHH - Hannover Medical School [Hannover]
13 Graduate School of Medicine [Osaka]
14 KU - Kanazawa University
15 Nagoya University
16 TGHRI - Toronto General Hospital Research Institute [Canada]
17 Shinshu University Hospital
18 University of Hyogo
19 Okayama University
20 Chulalongkorn University [Bangkok]
21 Erasmus MC - Erasmus University Medical Center [Rotterdam]
22 PKUPH - People's Hospital of Peking University
23 Academia Sinica
24 Kobe University
25 HKU - The University of Hong Kong
26 Nagoya City University [Nagoya, Japan]
2 Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology
3 Yonsei University
4 Pôle de Biologie Pathologie Génétique [CHU Lille]
5 Chiba University Hospital
6 Laboratoire de virologie [CHU Lille]
7 Azienda Ospedaliera Universitaria Pisana
8 UAB - Universitat Autònoma de Barcelona
9 KCH - King's College Hospital
10 UNITO - Università degli studi di Torino = University of Turin
11 SCU - Sichuan University [Chengdu]
12 MHH - Hannover Medical School [Hannover]
13 Graduate School of Medicine [Osaka]
14 KU - Kanazawa University
15 Nagoya University
16 TGHRI - Toronto General Hospital Research Institute [Canada]
17 Shinshu University Hospital
18 University of Hyogo
19 Okayama University
20 Chulalongkorn University [Bangkok]
21 Erasmus MC - Erasmus University Medical Center [Rotterdam]
22 PKUPH - People's Hospital of Peking University
23 Academia Sinica
24 Kobe University
25 HKU - The University of Hong Kong
26 Nagoya City University [Nagoya, Japan]
Sarah Feldman
- Function : Author
- PersonId : 768330
- ORCID : 0000-0001-8264-5184
Takeshi Matsui
- Function : Author
Hidenori Toyoda
- Function : Author
Lai Wei
- Function : Author
- PersonId : 771527
- ORCID : 0000-0002-6116-1671
Hiroshi Yatsuhashi
- Function : Author
Maud Lemoine
- Function : Author
- PersonId : 762597
- ORCID : 0000-0002-1322-5765
Yusuke Shimakawa
Connectez-vous pour contacter l'auteur
- Function : Correspondent author
- PersonId : 15324
- IdHAL : yusuke-shimakawa
- IdRef : 250394065
Connectez-vous pour contacter l'auteur
Abstract
Scale-up of tests and treatments is needed to eliminate hepatitis B virus (HBV) infection from resource-limited countries. However, access to nucleic acid tests that quantify HBV DNA, to determine treatment eligibility, is severely limited. We performed a systematic review and meta-analysis to assess the performance of the hepatitis B core-related antigen (HBcrAg) immunoassay, a low-cost (less than $15/assay) alternative to the nucleic acid test, to identify highly viremic patients, infected with any HBV genotype.
Origin : Files produced by the author(s)