The amyloid hypothesis of Alzheimer's disease at 25 years, EMBO Mol. Med, vol.8, pp.595-608, 2016. ,
Trafficking and proteolytic processing of APP. Cold Spring Harb, Perspect. Med, vol.2, pp.6270-006270, 2012. ,
An atomic structure of human ?-secretase, Nature, vol.525, pp.212-217, 2015. ,
Atomic-resolution structure of a disease-relevant A?(1-42) amyloid fibril, Proc. Natl Acad. Sci. USA, vol.113, pp.4976-4984, 2016. ,
Atomic resolution structure of monomorphic A?42 amyloid fibrils, J. Am. Chem. Soc, vol.138, pp.9663-9674, 2016. ,
Fibril structure of amyloid-?(1-42) by cryo-electron microscopy, Science, vol.358, pp.116-119, 2017. ,
Biochemically-defined pools of amyloid-? in sporadic Alzheimer's disease: correlation with amyloid PET, Brain, vol.140, pp.1486-1498, 2017. ,
Correlations of synaptic and pathological markers with cognition of the elderly, Neurobiol. Aging, vol.16, pp.298-304, 1995. ,
A Hexameric peptide barrel as building block of amyloid-? Protofibrils, Angew. Chem. Int. Ed, vol.53, pp.12756-12760, 2014. ,
Alzheimer's disease: soluble oligomeric A? (1-40) peptide in membrane mimic environment from solution NMR and circular dichroism studies, Neurochem Res, vol.29, pp.1-6, 2004. ,
Stabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptide, Biophys. J, vol.94, pp.2752-2766, 2008. ,
Structural characterization of a soluble amyloid ?-peptide oligomer, Biochemistry, vol.48, pp.1870-1877, 2009. ,
Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum, Proc. Natl Acad. Sci. USA, vol.90, pp.567-571, 1993. ,
Alzheimer amyloid a?1-42 channels: Effects of solvent, pH, and congo red, J. Neurosci. Res, vol.57, pp.458-466, 1999. ,
Amyloid beta protein forms ion channels: implications for Alzheimer's disease pathophysiology, FASEB J, vol.15, pp.2433-2444, 2001. ,
Amyloidogenic protein-membrane interactions: mechanistic insight from model systems, Angew. Chem. Int. Ed, vol.49, pp.5628-5654, 2010. ,
The toxic A? oligomer and Alzheimer's disease: an emperor in need of clothes, Nat. Neurosci, vol.15, pp.349-357, 2012. ,
A?42 assembles into specific ?-barrel pore-forming oligomers in membrane-mimicking environments, Proc. Natl Acad. Sci. USA, vol.113, pp.10866-10871, 2016. ,
Preparation of a well-defined and stable ?-barrel poreforming A?42 oligomer, Methods Mol. Biol, vol.1779, pp.13-22, 2018. ,
Amide proton temperature coefficients as hydrogen bond indicators in proteins, J. Biomol. NMR, vol.21, pp.249-261, 2001. ,
The Simshape Method for Protein-Detergent Interaction Research, Biophys. J, vol.114, p.679, 2018. ,
Hyphenation of size exclusion chromatography to native ion mobility mass spectrometry for the analytical characterization of therapeutic antibodies and related products, J. Chromatogr. B Anal. Technol. Biomed. Life Sci, vol.1086, pp.176-183, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02327936
Mass spectrometry of intact membrane protein complexes, Nat. Protoc, vol.8, pp.639-651, 2013. ,
Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes, Proc. Natl Acad. Sci. USA, vol.111, pp.9455-9460, 2014. ,
Di-Tyrosine cross-link decreases the collisional cross-section of A? peptide dimers and trimers in the gas phase: an ion mobility study, PLoS ONE, vol.9, pp.100200-100214, 2014. ,
Intrinsically disordered p53 and its complexes populate compact conformations in the gas phase, Angew. Chem. Int. Ed. Engl, vol.52, pp.361-365, 2013. ,
Molecular dynamics simulations of a membrane protein-micelle complex in vacuo, J. Am. Chem. Soc, vol.131, pp.16606-16607, 2009. ,
Transmembrane structures for Alzheimer's A?(1-42) oligomers, J. Am. Chem. Soc, vol.132, pp.13300-13312, 2010. ,
How the amyloid-? peptide and membranes affect each other: an extensive simulation study, Biochim. Biophys. Acta, vol.1828, pp.327-339, 2013. ,
Analysis of single nucleic acid molecules with protein nanopores, Methods Enzymol, vol.475, pp.591-623, 2010. ,
Engineered bacterial outer membrane vesicles with enhanced functionality, J. Mol. Biol, vol.380, pp.51-66, 2008. ,
Membrane-bound dynamic structure of an arginine-rich cell-penetrating peptide, the protein transduction domain of HIV TAT, from solid-state NMR, Biochemistry, vol.49, pp.6009-6020, 2010. ,
The levels of water-soluble and triton-soluble A? are increased in Alzheimer's disease brain, Brain Res, vol.1450, pp.138-147, 2012. ,
Molecular mechanism of action of ?-hairpin antimicrobial peptide arenicin: oligomeric structure in dodecylphosphocholine micelles and pore formation in planar lipid bilayers, Biochemistry, vol.50, pp.6255-6265, 2011. ,
The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide, PLoS ONE, vol.5, p.9505, 2010. ,
Amyloid-? peptide protects against microbial infection in mouse and worm models of Alzheimer's disease, Sci. Transl. Med, vol.8, pp.340-72, 2016. ,
Is arginine charged in a membrane?, Biophys. J, vol.94, pp.11-13, 2008. ,
Side-chain hydrophobicity scale derived from transmembrane protein folding into lipid bilayers, Proc. Natl Acad. Sci. USA, vol.108, pp.10174-10177, 2011. ,
A facile method for expression and purification of the Alzheimer's disease-associated amyloid beta-peptide, FEBS J, vol.276, pp.1266-1281, 2009. ,
Expression, purification and crystallization of a lyssavirus matrix (M) protein, Acta Crystallogr. Sect. F. Struct. Biol. Cryst. Commun, vol.64, pp.258-262, 2008. ,
Alzheimer´s disease-associated A?42 peptide: expression and purification for NMR structural studies, Curr. Chem. Biol, vol.11, pp.50-62, 2017. ,
Scrambling free combinatorial labeling of alanine-?, isoleucine-?1, leucine-proS and valine-proS methyl groups for the detection of long range NOEs, J. Biomol. NMR, vol.61, pp.73-82, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01119770
Solution NMR of membrane proteins: practice and challenges, Magn. Reson. Chem, vol.44, pp.24-40, 2006. ,
15)N and (13)C-SOFAST-HMQC editing enhances 3D-NOESY sensitivity in highly deuterated, selectively [(1)H,(13)C]-labeled proteins, J. Biomol. NMR, vol.66, pp.259-271, 2016. ,
The causality principle in the reconstruction of sparse NMR spectra, Chem. Commun, vol.50, pp.8947-8950, 2014. ,
Analysis of non-uniformly sampled spectra with multi-dimensional decomposition, Prog. Nucl. Magn. Reson. Spectrosc, vol.59, pp.271-292, 2011. ,
Solution structures of micellebound amyloid beta-(1-40) and beta-(1-42) peptides of Alzheimer's disease, J. Mol. Biol, vol.285, pp.755-773, 1999. ,
Version 1.2 of the Crystallography and NMR system, Nat. Protoc, vol.2, pp.2728-2733, 2007. ,
ARIA2: automated NOE assignment and data integration in NMR structure calculation, Bioinformatics, vol.23, pp.381-382, 2007. ,
Protein backbone and sidechain torsion angles predicted from NMR chemical shifts using artificial neural networks, J. Biomol. NMR, vol.56, pp.227-241, 2013. ,
Refinement of protein structures in explicit solvent, Proteins, vol.50, pp.496-506, 2003. ,
PROCHECK: a program to check the stereochemical quality of protein structures, J. Appl. Cryst, vol.26, pp.283-291, 1993. ,
WHAT IF: a molecular modeling and drug design program, J. Mol. Graph, vol.8, pp.52-56, 2001. ,
MolProbity: all-atom contacts and structure validation for proteins and nucleic acids, Nucleic Acids Res, vol.35, pp.375-383, 2007. ,
Recommendations for reporting ion mobility Mass Spectrometry measurements, Mass Spectrom. Rev, 2019. ,
URL : https://hal.archives-ouvertes.fr/hal-02012317
Theory of plasma chromatography/gaseous electrophoresis, Anal. Chem, vol.47, pp.970-983, 1975. ,
Collision cross sections of proteins and their complexes: a calibration framework and database for gas-phase structural biology, Anal. Chem, vol.82, pp.9557-9565, 2010. ,
Collision cross sections for structural proteomics, Structure, vol.23, pp.791-799, 2015. ,
A Robust, detergent-friendly method for mass spectrometric analysis of integral membrane proteins, Anal. Chem, vol.72, pp.5655-5658, 2000. ,
URL : https://hal.archives-ouvertes.fr/hal-02150358
CHARMM-GUI: a web-based graphical user interface for CHARMM, J. computational Chem, vol.29, pp.1859-1865, 2008. ,
MDTraj: a modern open library for the analysis of molecular dynamics trajectories, Biophys. J, vol.109, pp.1528-1532, 2015. ,