,
Long-term control of HIV by CCR5 Delta32/Delta32 559 stem-cell transplantation, N Engl J Med, vol.360, pp.692-698, 2009. ,
,
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed 562 individuals to HIV-1 infection, Cell, vol.86, pp.367-377, 1996. ,
, , p.564
,
Resistance to HIV-1 infection in caucasian 566 individuals bearing mutant alleles of the CCR-5 chemokine receptor gene, Nature, vol.382, pp.722-725, 1996. ,
, , p.568
,
,
,
Late cytomegalovirus disease and mortality in recipients of allogeneic 609 hematopoietic stem cell transplants: importance of viral load and T-cell immunity, Blood, vol.101, p.15, 2003. ,
Long-term surveillance of haematopoietic stem cell 611 recipients with resolved hepatitis B: high risk of viral reactivation even in a recipient with a vaccinated donor, J 612 Viral Hepat, vol.14, pp.478-483, 2007. ,
,
, J. J, p.615
EBV) reactivation is a frequent event after allogeneic stem cell transplantation 616 (SCT) and quantitatively predicts EBV-lymphoproliferative disease following T-cell--depleted SCT, Blood, vol.98, pp.972-617, 2001. ,
T cells for viral infections after allogeneic hematopoietic stem cell transplant, Blood, vol.619, pp.3331-3340, 2016. ,
Antiviral T-cell therapy, Immunol Rev, vol.258, p.19, 2014. ,
Cellular immunotherapy for viral infection after HSC transplantation, Nat Rev 622 Immunol, vol.5, pp.9-20, 2005. ,
,
, , p.625
, Antiretroviral-free HIV-1 remission and viral rebound after allogeneic stem cell transplantation: report of 2 cases
, Ann Intern Med, vol.161, pp.319-327, 2014.
,
Transplantation of 629 CCR532 Homozygous Umbilical Cord Blood in a Child With Acute Lymphoblastic Leukemia and Perinatally 630 ,
, Acquired HIV Infection. Open forum infectious diseases, vol.5, p.90, 2018.
, HIV cure research: advances and prospects. Virology 454-455, p.632, 2014.
URL : https://hal.archives-ouvertes.fr/pasteur-01420527
, , p.634
,
,
Peripheral Blood versus Bone Marrow from Unrelated Donors: 637 Bone Marrow Allografts Have Improved Long-Term Overall and Graft-versus-Host Disease-Free, p.638 ,
, Survival. Biol Blood Marrow Transplant, vol.25, pp.270-278, 2019.
, , p.640
, , p.641
, , p.642
Marrow Transplant Clinical Trials, Peripheral-blood stem cells versus bone 643 marrow from unrelated donors, N Engl J Med, vol.367, p.25, 2012. ,
, , p.645
, , p.646
, , p.647
, Allogeneic Hematopoietic Cell Transplant for HIV Patients with Hematologic Malignancies: the BMT CTN-648
, Trial. Biol Blood Marrow Transplant, 2019.
Allogeneic haematopoietic stem cell transplantation in patients with human 650 immunodeficiency virus: the experiences of more than 25 years, Clin Exp Immunol, vol.163, p.27, 2011. ,
Immune 652 Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation, Front Immunol, vol.7, p.28, 2016. ,
Immune reconstitution following stem cell transplantation ,
, Hematology Am Soc Hematol Educ Program, pp.215-219, 2015.
, , p.656
Lymphocyte reconstitution following allogeneic hematopoietic stem cell transplantation: a 657 retrospective study including 148 patients, Bone Marrow Transplant, vol.39, pp.613-622, 2007. ,
Immune reconstitution following hematopoietic progenitor cell transplantation: 659 challenges for the future, Bone Marrow Transplant, vol.35, pp.53-57, 2005. ,
Thymic T-cell development in allogeneic stem cell 661 transplantation, Blood, vol.117, pp.6768-6776, 2011. ,
Homeostasis of naive and memory T cells, Immunity, vol.29, pp.848-862, 2008. ,
Programmed death-1 (PD-1) defines a transient and 664 dysfunctional oligoclonal T cell population in acute homeostatic proliferation, J Exp Med, vol.204, p.34, 2007. ,
,
,
Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in 668 regulating graft-versus-host disease lethality, Blood, vol.122, pp.3062-3073, 2013. ,
,
,
, , p.672
, , p.673
, Integrin alpha4beta7 expression on peripheral blood CD4(+) T cells predicts HIV acquisition and disease 674 progression outcomes, Sci Transl Med, vol.10, 2018.
, , p.676
HIV nonprogressors preferentially maintain highly 677 functional HIV-specific CD8+ T cells, Blood, vol.107, pp.4781-4789, 2006. ,
, , p.679
Dynamics of T cell responses in HIV infection, J Immunol, vol.168, p.680, 2002. ,
,
Impact of donor CMV status on viral infection and 683 reconstitution of multifunction CMV-specific T cells in CMV-positive transplant recipients, Blood, vol.113, pp.6465-6476, 2009. ,
, Immune Reconstitution after Allogeneic, vol.686
, Hematopoietic Stem Cell Transplantation: Time To T Up the Thymus, J Immunol, vol.198, p.40, 2017.
The thymus during HIV disease: role in pathogenesis and in immune 688 recovery, Current HIV research, vol.2, pp.177-183, 2004. ,
, , p.690
Activation and expansion of CD8(+) T effector cells in patients with chronic 691 graft-versus-host disease, Biol Blood Marrow Transplant, vol.17, pp.1121-1132, 2011. ,
,
CD38(bright)CD8(+) T Cells Associated with the 694 Development of Acute GVHD Are Activated, Proliferating, and Cytotoxic Trafficking Cells, Biol Blood Marrow, vol.695, 2019. ,
,
Activation-associated phenotype of CD3 T cells in acute graft-versus-host disease, Clin Exp Immunol, vol.145, pp.36-43, 2006. ,
,
,
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation, Nat Med, vol.15, pp.893-900, 2009. ,
,
, , p.705
,
Clonally expanded CD4+ T cells can produce 707 infectious HIV-1 in vivo, Proc Natl Acad Sci U S A, vol.113, pp.1883-1888, 2016. ,
, , p.709
Clinical and immunologic impact of CCR5 blockade in graft-710 versus-host disease prophylaxis, Blood, vol.129, pp.906-916, 2017. ,
,
Generation of HIV-1-specific CD8+ cell responses following allogeneic 713 hematopoietic cell transplantation, Blood, vol.112, pp.3484-3487, 2008. ,
, , p.715
, , p.716
,
,
Evidence for persistence of the SHIV reservoir early after MHC 719 haploidentical hematopoietic stem cell transplantation, Nat Commun, vol.9, p.4438, 2018. ,
,
Immune donors can protect marrow-transplant recipients from severe cytomegalovirus 722 infections, Lancet, vol.1, pp.774-776, 1987. ,
Clearance of persistent 724 hepatitis B virus infection in Chinese bone marrow transplant recipients whose donors were anti-hepatitis B core-725 and anti-hepatitis B surface antibody-positive, J Infect Dis, vol.178, p.51, 1998. ,
How I treat and monitor viral hepatitis B infection in patients receiving intensive 727 immunosuppressive therapies or undergoing hematopoietic stem cell transplantation, Blood, vol.113, p.52, 2009. ,
Cytotoxic T-lymphocyte response to 729 cytomegalovirus after human allogeneic bone marrow transplantation: pattern of recovery and correlation with 730 cytomegalovirus infection and disease, Blood, vol.78, pp.1373-1380, 1991. ,
, , p.732
CD8+ TCR repertoire formation is guided 733 primarily by the peptide component of the antigenic complex, J Immunol, vol.190, pp.931-939, 2013. ,
, Mechanisms behind functional avidity maturation in T cells
, Clin Dev Immunol, vol.2012, p.163453, 2012.
, , p.737
, Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for 738 HIV, PLoS Pathog, vol.12, p.1005535, 2016.
, , p.740
, CROI, vol.741, p.57, 2019.
,
, CROI, 2020.
, , p.744
, Hematopoietic Stem Cell Transplantation as a Platform for Post-Transplantation Cellular Therapy, Biol Blood 745 Marrow Transplant, vol.21, pp.1714-1720, 2015.
,
, , p.748
CMV-specific T cells generated from naive T cells recognize 749 atypical epitopes and may be protective in vivo, Sci Transl Med, vol.7, pp.285-263, 2015. ,
Strategies of adoptive T -cell transfer to 751 treat refractory viral infections post allogeneic stem cell transplantation, J Hematol Oncol, vol.12, p.61, 2019. ,
Broadly neutralizing anti-HIV-1 monoclonal antibodies in the 753 clinic, Nat Med, vol.25, pp.547-553, 2019. ,
, , p.755
Switching From 756 a Protease Inhibitor-based Regimen to a Dolutegravir-based Regimen: A Randomized Clinical Trial to Determine 757 the Effect on Peripheral Blood and Ileum Biopsies From Antiretroviral Therapy-suppressed Human 758 Immunodeficiency Virus-infected Individuals, Clin Infect Dis, vol.69, pp.1320-1328, 2019. ,
, , p.760
, Standardization and performance evaluation of "modified" and "ultrasensitive" versions of the Abbott RealTime 761 HIV-1 assay, adapted to quantify minimal residual viremia, J Clin Virol, vol.52, pp.17-22, 2011.
,
Development of sensitive ddPCR assays to reliably quantify the proviral DNA reservoir in 764 all common circulating HIV subtypes and recombinant forms, J Int AIDS Soc, vol.21, p.25185, 2018. ,
,
Partial recovery of senescence and differentiation disturbances in CD8(+) T cell effector-memory 767 cells in HIV-1 infection after initiation of anti-retroviral treatment, Clin Exp Immunol, vol.186, p.66, 2016. ,
, , p.769
Lymphocyte activation antigens. I. A monoclonal antibody, anti-Act I, defines a new late lymphocyte 770 activation antigen, J Immunol, vol.133, pp.1857-1862, 1984. ,
Central memory and effector memory T cell subsets: function, 772 generation, and maintenance, Annu Rev Immunol, vol.22, pp.745-763, 2004. ,