Adherence to preventive measures after splenectomy in the hospital setting and in the community

Hélène Coignard-Biehler (1) , Fanny Lanternier (1) , Arnaud Hot (2, 3) , Dominique Salmon (4, 5) , Anne Berger (6, 4) , Marianne de Montalembert (4, 7) , Felipe Suarez (8, 4) , Odile Launay (5, 4) , Marc Lecuit (4, 8, 9, 10) , Olivier Lortholary (1, 4, 10)

1 Centre d'infectiologie Necker-Pasteur [CHU Necker]
2 Hôpital Edouard Herriot [CHU - HCL]
3 UCBL - Université Claude Bernard Lyon 1
4 UPD5 - Université Paris Descartes - Paris 5
5 Hôpital Cochin [AP-HP]
6 HEGP - Hôpital Européen Georges Pompidou [APHP]
7 Service de pédiatrie générale [CHU Necker]
8 Hôpital Necker - Enfants Malades [AP-HP]
9 Service des Maladies infectieuses et tropicales [CHU Necker]
10 IP - Institut Pasteur [Paris]

Overwhelming post-splenectomy infection (OPSI) remains a long-term risk in asplenic patients, which may be reduced by appropriate preventive measures. Specific guidelines have been developed to lower its incidence. Aims: To assess the implementation of guidelines by specialized physicians of a university hospital and primary care physicians. Methods: A retrospective review of splenectomized patients' medical files over a six year period was carried out. Patients' general practitioners were contacted and a questionnaire was sent to them. Results: 154 individuals who underwent splenectomy between 2000 and 2005 were eligible (62 children and 92 adults): 70.8%

Mots clés: Prevention; Infection; Splenectomy; Immunization

Domaines: Sciences du Vivant [q-bio]; Médecine humaine et pathologie; Maladies infectieuses; Immunologie; Microbiologie et Parasitologie

Hélène Coignard-Biehler, Fanny Lanternier, Arnaud Hot, Dominique Salmon, Anne Berger, et al.. Adherence to preventive measures after splenectomy in the hospital setting and in the community. Journal of Infection and Public Health, 2011, 4 (4), pp.187-194. ⟨10.1016/j.jiph.2011.06.004⟩. ⟨pasteur-02870113⟩