Grasping at Shadows: Revealing the Elusive Nature of Essential Genes

Tarek Msadek (1)

1 Biologie des Bactéries Pathogènes à Gram-positif

The conundrum of studying a gene that is essential for bacterial viability poses a nontrivial genetic challenge that has been met with mixed success using multiple strategies. Most of the time, cursory analyses merely report the inability to inactivate a gene of interest, hence suggesting it is vital for the cell [...]

Domains: Life Sciences [q-bio]; Life Sciences [q-bio]; Microbiology and Parasitology

Tarek Msadek. Grasping at Shadows: Revealing the Elusive Nature of Essential Genes. Journal of Bacteriology, 2009, 191 (15), pp.4701-4704. ⟨10.1128/JB.00572-09⟩. ⟨pasteur-02870042⟩