Inadequate management of pregnancy-associated listeriosis: lessons from four case reports

C. Charlier (1, 2, 3, 4, 5, 6) , F. Goffinet (7) , E. Azria (8) , A. Leclercq (1, 2, 9) , M. Lecuit (9, 1, 2, 3, 4, 5, 6)

1 CNRL - Centre National de Référence Listeria - National Reference Center Listeria
2 CC-OMS / WHO-CC - Centre collaborateur de l'OMS Listeria / WHO Collaborating Centre Listeria
3 UPD5 - Université Paris Descartes - Paris 5
4 Hôpital Necker - Enfants Malades [AP-HP]
5 Service des Maladies infectieuses et tropicales [CHU Necker]
6 Imagine - U1163 - Imagine - Institut des maladies génétiques (IHU)
7 Service de Gynécologie et Obstétrique [Cochin]
8 Service de Gynécologie - Obstétrique [CHU Bichat]
9 Biologie des Infections - Biology of Infection

Listeria monocytogenes infection during pregnancy can lead to dramatic fetal or neonatal outcomes. No clinical trial has evaluated treatment options, and retrospective studies of cases are therefore important to define optimal regimens. We report four cases of materno-neonatal listeriosis illustrating inadequate antimicrobial therapy management and discuss recommended treatment options.

Mots clés: Amoxicillin; infant; Listeria monocytogenes; listeriosis; pregnancy

Domaines: Sciences du Vivant [q-bio]; Médecine humaine et pathologie; Maladies infectieuses; Microbiologie et Parasitologie; Bactériologie

C. Charlier, F. Goffinet, E. Azria, A. Leclercq, M. Lecuit. Inadequate management of pregnancy-associated listeriosis: lessons from four case reports. Clinical Microbiology and Infection, 2014, 20 (3), pp.246-249. ⟨10.1111/1469-0691.12281⟩. ⟨pasteur-02869853⟩