Epidemiology, Diagnosis and Risk Factors of Helicobacter pylori Infection - Archive ouverte HAL Access content directly
Book Sections Year : 2019

Epidemiology, Diagnosis and Risk Factors of Helicobacter pylori Infection

Epidémiologie, Diagnostic at facteurs de risque de l'infection par Helicobacter pylori

(1) , (1) , (2)
1
2

Abstract

Helicobacter pylori is a human-specific pathogen , which leads to gastric pathologies including gastric cancer. It is a highly unique bacterium considered as a carcinogenic agent. H. pylori remains a major human health problem , responsible for~90% of the gastric cancer cases. Approximately four billion individuals have been detected for H. pylori infection worldwide in 2015. At the turn of the twenty-first century, the prevalence of H. pylori has been declining in highly industrialized countries of the Western world, whereas prevalence has plateaued at a high level in developing and newly industrialized countries. However, the infection status remains high in immigrants coming from countries with high prevalence of H. pylori infection. H. pylori can be diagnosed both by invasive and non-invasive methods. Urea breath test and stool antigens detection are among the most commonly used non-invasive ones. Although the way H. pylori is transmitted remains still not fully clear, the level of contamination is strongly dependent on the familial and environmental context, with a drastic impact of living conditions with poor hygiene and sanitation. However, familial socioeconomic status is the main risk factor for H. pylori infection among children. In addition, food and water source have a high impact on the prevalence of H. pylori infection worldwide. This chapter highlights the latest knowledge in the epidemiology of H. pylori infection, its diagnosis and critical risk factors responsible for its high prevalence in some populations and geographic areas.
Fichier principal
Vignette du fichier
Kotilea et al Adv Exp Med Biol. 2019;.pdf (8.81 Mo) Télécharger le fichier
Origin : Files produced by the author(s)
Loading...

Dates and versions

pasteur-02868133 , version 1 (11-08-2020)

Identifiers

Cite

Kallirroi Kotilea, Patrick Bontems, Eliette Touati. Epidemiology, Diagnosis and Risk Factors of Helicobacter pylori Infection. Shigeru Kamiya; Steffen Backert. Helicobacter pylori in human diseases, Springer Nature, pp.17-33, 2019, 978-3-030-21915-4. ⟨10.1007/5584_2019_357⟩. ⟨pasteur-02868133⟩

Collections

PASTEUR
58 View
973 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More