The complete mitochondrial genome sequence of the pathogenic yeast Candida ( Torulopsis ) glabrata

Romain Koszul (1) , Alain Malpertuy (1) , Lionel Frangeul (2) , Christiane Bouchier (3) , Patrick Wincker (4) , Agnès Thierry (1) , Stéphanie Duthoy (3) , Stéphane Ferris (3) , Christophe Hennequin (1, 5) , Bernard Dujon (1)

1 Génétique Moléculaire des Levures
2 PF4 - Intégration et Analyse Génomique (Plate-Forme 4)
3 Génomique (Plate-Forme) - Genomics Platform
4 GENOSCOPE - Genoscope - Centre national de séquençage [Evry]
5 Laboratoire de parasitologie et de mycologie médicales [CHU Amiens]

We report here the complete sequence of the mitochondrial (mt) genome of the pathogenic yeast Candida glabrata . This 20 kb mt genome is the smallest among sequenced hemiascomycetous yeasts. Despite its compaction, the mt genome contains the genes encoding the apocytochrome b (COB ), three subunits of ATP synthetase (ATP6 , 8 and 9 ), three subunits of cytochrome oxidase (COX1 , 2 and 3 ), the ribosomal protein VAR1 , 23 tRNAs, small and large ribosomal RNAs and the RNA subunit of RNase P. Three group I introns each with an intronic open reading frame are present in the COX1 gene. This sequence is available under accession number AJ511533.

Domains: Life Sciences [q-bio]

Romain Koszul, Alain Malpertuy, Lionel Frangeul, Christiane Bouchier, Patrick Wincker, et al.. The complete mitochondrial genome sequence of the pathogenic yeast Candida ( Torulopsis ) glabrata. FEBS Letters, 2003, 534 (1-3), pp.39-48. ⟨10.1016/s0014-5793(02)03749-3⟩. ⟨pasteur-02868102⟩