Overcoming natural replication barriers: differential helicase requirements, Nucleic Acids Res, vol.40, pp.1091-1105, 2012. ,
CGG/CCG repeats exhibit orientation-dependent instability and orientation-independent fragility in Saccharomyces cerevisiae, Hum Mol Genet, vol.9, pp.93-100, 2000. ,
A highly specific SpCas9 variant is identified by in vivo screening in yeast, Nat. Biotechnol, vol.36, pp.265-271, 2018. ,
CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair, Nat. Commun, vol.9, p.1133, 2018. ,
URL : https://hal.archives-ouvertes.fr/inserm-02156427
RPA coordinates DNA end resection and prevents formation of DNA hairpins, Mol Cell, vol.50, pp.589-600, 2013. ,
Enhanced proofreading governs CRISPR-Cas9 targeting accuracy, Nature, vol.550, pp.407-410, 2017. ,
Contracting CAG/CTG repeats using the CRISPR-Cas9 nickase, Nat. Commun, vol.7, p.13272, 2016. ,
A framework for variation discovery and genotyping using next-generation DNA sequencing data, Nat Genet, vol.43, pp.491-498, 2011. ,
Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems, Nucleic Acids Res, vol.41, pp.4336-4343, 2013. ,
Consequences of unique double-stranded breaks in yeast chromosomes: death or homozygosis, Mol Gen Genet, vol.240, pp.170-180, 1993. ,
Abundant microsatellite polymorphism in Saccharomyces cerevisiae, and the different distributions of microsatellites in eight prokaryotes and S. cerevisiae, result from strong mutation pressures and a variety of selective forces, Proc Natl Acad Sci, vol.95, pp.1647-1652, 1998. ,
NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the Ligase IV pathway, Genes&Development, vol.15, pp.3005-3012, 2001. ,
Expansion and lengthdependent fragility of CTG repeats in yeast, Science, vol.279, pp.853-856, 1998. ,
Accurate typing of short tandem repeats from genome-wide sequencing data and its applications, Genome Res, 2015. ,
Trinucleotide repeats that expand in human disease form hairpin structures in vitro, Cell, vol.81, pp.533-540, 1995. ,
In vivo biochemistry: physical monitoring of recombination induced by site-specific endonucleases, BioEssays, vol.17, pp.609-620, 1995. ,
The many interfaces of Mre11, Cell, vol.95, pp.583-586, 1998. ,
Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR, Genome Biol, vol.17, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01346049
Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases, Nature, vol.96, pp.931-945, 1999. ,
High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide offtarget effects, Nature, vol.529, pp.490-495, 2016. ,
VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing, Genome Res, vol.22, pp.568-576, 2012. ,
Recombination proteins in yeast, Annu. Rev. Genet, vol.38, pp.233-271, 2004. ,
Directed evolution of CRISPR-Cas9 to increase its specificity, Nat. Commun, vol.9, p.3048, 2018. ,
CRISPR/Cas9 cleavages in budding yeast reveal templated insertions and strand-specific insertion/deletion profiles, Proc. Natl. Acad. Sci, vol.115, pp.2040-2047, 2018. ,
Sae2 Is an Endonuclease that Processes Hairpin DNA Cooperatively with the Mre11/Rad50/Xrs2 Complex, Mol. Cell, vol.28, pp.638-651, 2007. ,
Fast and accurate short read alignment with Burrows-Wheeler transform, Bioinforma. Oxf. Engl, vol.25, pp.1754-1760, 2009. ,
The Sequence Alignment/Map format and SAMtools, Bioinformatics, vol.25, pp.2078-2079, 2009. ,
Analysis of microsatellites in 13 hemiascomycetous yeast species: mechanisms involved in genome dynamics, J. Mol. Evol, vol.56, pp.730-741, 2003. ,
Sae2, Exo1 and Sgs1 collaborate in DNA doublestrand break processing, Nature, vol.455, pp.770-774, 2008. ,
TALENinduced double-strand break repair of CTG trinucleotide repeats, Cell Rep, vol.22, pp.2146-2159, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01727334
Assembling large DNA segments in yeast, Methods Mol. Biol. Clifton NJ, vol.852, pp.133-150, 2012. ,
, Situ Visualization of DNA Double-Strand Break Repair in Human Fibroblasts, vol.280, pp.590-592, 1998.
Differential requirement of Srs2 helicase and Rad51 displacement activities in replication of hairpin-forming CAG/CTG repeats, Nucleic Acids Res, vol.45, pp.4519-4531 ,
URL : https://hal.archives-ouvertes.fr/hal-01526732
Trinucleotide repeat disorders, Annu Rev Neurosci, vol.30, pp.575-621, 2007. ,
Yeast transformation: a model system for the study of recombination, Proc. Natl. Acad. Sci. U. S. A, vol.78, pp.6354-6358, 1981. ,
DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks, Mol. Cell, vol.63, pp.633-646, 2016. ,
Replication and expansion of trinucleotide repeats in yeast, Mol Cell Biol, vol.23, pp.1349-1357, 2003. ,
Site-specific recombination determined by I-Sce I, a mitochondrial group I intron-encoded endonuclease expressed in the yeast nucleus, Genetics, vol.130, pp.451-460, 1992. ,
Distribution and variability of trinucleotide repeats in the genome of the yeast Saccharomyces cerevisiae, Gene, vol.174, pp.165-174, 1996. ,
Double-strand break repair can lead to high frequencies of deletions within short CAG/CTG trinucleotide repeats, Mol Gen Genet, vol.261, pp.871-882, 1999. ,
Trinucleotide repeats and other microsatellites in yeasts, Res Microbiol, vol.150, pp.589-602, 1999. ,
Recombinationinduced CAG trinucleotide repeat expansions in yeast involve the MRE11/RAD50/XRS2 complex, EMBO J, vol.19, pp.2381-2390, 2000. ,
Contractions and expansions of CAG/CTG trinucleotide repeats occur during ectopic gene conversion in yeast, by a MUS81-independent mechanism, J. Mol. Biol, vol.326, pp.769-782, 2003. ,
Comparative genomics and molecular dynamics of DNA repeats in eukaryotes, Microbiol Mol Biol Rev, vol.72, pp.686-727, 2008. ,
Highly specific contractions of a single CAG/CTG trinucleotide repeat by TALEN in yeast, PLoS ONE, vol.9, p.95611, 2014. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01370694
Concerted deletions and inversions are caused by mitotic recombination between delta sequences in Saccharomyces cerevisiae, Mol Cell Biol, vol.7, pp.1198-1207, 1987. ,
Trinucleotide repeats affect DNA replication in vivo, Nat. Genet, vol.17, pp.298-304, 1997. ,
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae, Genetics, vol.122, pp.19-27, 1989. ,
Rationally engineered Cas9 nucleases with improved specificity, Science, vol.351, pp.84-88, 2016. ,
DSB structure impacts DNA recombination leading to class switching and chromosomal translocations in human B cells, PLOS Genet, vol.15, p.1008101, 2019. ,
RNAtemplated DNA repair, Nature, vol.447, pp.338-341, 2007. ,
Fragile sites still breaking, Trends Genet, vol.14, pp.501-506, 1998. ,
Replication stalling and heteroduplex formation within CAG/CTG trinucleotide repeats by mismatch repair, DNA Repair, vol.42, pp.94-106, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01299733
A fast, sensitive and cost-effective method for nucleic acid detection using nonradioactive probes, Biol. Methods Protoc, vol.3, 2018. ,
URL : https://hal.archives-ouvertes.fr/pasteur-02864565
Involvement of very short DNA tandem repeats and the influence of the RAD52 gene on the occurrence of deletions in Saccharomyces cerevisiae, Genetics, vol.156, pp.549-557, 2000. ,
Yeast DNA ligase IV mediates nonhomologous DNA end joining, Nature, vol.388, pp.495-498, 1997. ,
Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends, Cell, vol.134, pp.981-994, 2008. ,