Analogues structuraux de la serotonine comme marqueurs d'affinite des recepteurs serotoninergiques
Abstract
Derivatives of serotonine and bufotenine are synthesized as potential electrophilic or photoactivable labels for the serotoninergic sites. The most promising compound is the azidoethyl-3 indole derivative 13 which presents a high affinity for the site; the corresponding binding appears specific and irreversible after photoactivation.