Analogues structuraux de la serotonine comme marqueurs d'affinite des recepteurs serotoninergiques

Abstract : Derivatives of serotonine and bufotenine are synthesized as potential electrophilic or photoactivable labels for the serotoninergic sites. The most promising compound is the azidoethyl-3 indole derivative 13 which presents a high affinity for the site; the corresponding binding appears specific and irreversible after photoactivation.