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Vector-Borne Transmission of the Zika Virus Asian Genotype in Europe

Abstract : Three autochthonous cases of Zika virus occurred in southern France in August 2019. Diagnosis relied on serology and transcription-mediated amplification. Attempts for virus isolation and ZIKV genome RT-PCR detection remained negative. Since the index case was not identified, we addressed the issue of genotyping and geographical origin by performing hemi-nested PCR and sequencing in the Pr gene. Analysis of 16 genotype-specific Single Nucleotides Polymorphisms identified the Asian genotype and suggested a Southeast Asia origin.
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Submitted on : Thursday, May 28, 2020 - 5:02:52 PM
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Guillaume Durand, Géraldine Piorkowski, Laurence Thirion, Laetitia Ninove, Sandra Giron, et al.. Vector-Borne Transmission of the Zika Virus Asian Genotype in Europe. Viruses, MDPI, 2020, 12 (3), pp.296. ⟨10.3390/v12030296⟩. ⟨pasteur-02641461⟩

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