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Journal Articles Viruses Year : 2020

Vector-Borne Transmission of the Zika Virus Asian Genotype in Europe

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Géraldine Piorkowski
  • Function : Author
  • PersonId : 1056588
Laurence Thirion
  • Function : Author
  • PersonId : 1064241
Xavier de Lamballerie
  • Function : Author
  • PersonId : 952950

Abstract

Three autochthonous cases of Zika virus occurred in southern France in August 2019. Diagnosis relied on serology and transcription-mediated amplification. Attempts for virus isolation and ZIKV genome RT-PCR detection remained negative. Since the index case was not identified, we addressed the issue of genotyping and geographical origin by performing hemi-nested PCR and sequencing in the Pr gene. Analysis of 16 genotype-specific Single Nucleotides Polymorphisms identified the Asian genotype and suggested a Southeast Asia origin.
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Dates and versions

pasteur-02641461 , version 1 (28-05-2020)

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Attribution - CC BY 4.0

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Guillaume Durand, Géraldine Piorkowski, Laurence Thirion, Laetitia Ninove, Sandra Giron, et al.. Vector-Borne Transmission of the Zika Virus Asian Genotype in Europe. Viruses, 2020, 12 (3), pp.296. ⟨10.3390/v12030296⟩. ⟨pasteur-02641461⟩
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