Skip to Main content Skip to Navigation
Journal articles

Inhibitory IgG Receptor-Expressing Cells: The Must-Have Accessory for Anti-CD40 Immunomodulatory mAb Efficacy

Abstract : In this issue of Cancer Cell, Dahan and colleagues demonstrate that modified Fc regions of agonistic anti-human CD40 mAbs can drastically increase their efficiency in a mouse pre-clinical model expressing human CD40 and IgG receptors. This study also highlights the fine balance between increased treatment efficacy and secondary side effects.
Document type :
Journal articles
Complete list of metadata

https://hal-pasteur.archives-ouvertes.fr/pasteur-02578652
Contributor : Marie Martin <>
Submitted on : Tuesday, November 3, 2020 - 1:28:10 PM
Last modification on : Wednesday, June 2, 2021 - 4:26:36 PM
Long-term archiving on: : Thursday, February 4, 2021 - 6:32:19 PM

File

Cancer Cell PREVIEW for HAL PA...
Files produced by the author(s)

Licence


Distributed under a Creative Commons Attribution - NonCommercial - NoDerivatives 4.0 International License

Identifiers

Citation

Pierre Bruhns, Jean-Luc Teillaud. Inhibitory IgG Receptor-Expressing Cells: The Must-Have Accessory for Anti-CD40 Immunomodulatory mAb Efficacy. Cancer Cell, Elsevier, 2016, 29 (6), pp.771-773. ⟨10.1016/j.ccell.2016.05.009⟩. ⟨pasteur-02578652⟩

Share

Metrics

Record views

95

Files downloads

124