H. Valdez and M. M. Lederman, Cytokines and cytokine therapies in HIV infection, AIDS Clin Rev, pp.187-228, 1997.

P. Borrow, H. Lewicki, B. H. Hahn, G. M. Shaw, and M. B. Oldstone, Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection, J Virol, vol.68, issue.9, pp.6103-6113, 1994.

J. O. Kahn and B. D. Walker, Acute human immunodeficiency virus type 1 infection, N Engl J Med, vol.339, issue.1, pp.33-42, 1998.

M. S. Cohen, G. M. Shaw, A. J. Mcmichael, and B. F. Haynes, Acute HIV-1 infection, N Engl J Med, vol.364, issue.20, pp.1943-54, 2011.

S. G. Deeks, C. M. Kitchen, L. Liu, H. Guo, R. Gascon et al., Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load, Blood, vol.104, issue.4, pp.942-949, 2004.

P. W. Hunt, J. N. Martin, E. Sinclair, B. Bredt, E. Hagos et al., T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy, J Infect Dis, vol.187, issue.10, pp.1534-1577, 2003.

G. K. Robbins, J. G. Spritzler, E. S. Chan, D. M. Asmuth, R. T. Gandhi et al., Incomplete reconstitution of T cell subsets on combination antiretroviral therapy in the AIDS Clinical Trials Group protocol 384, Clin Infect Dis, vol.48, issue.3, pp.350-61, 2009.

S. Read, V. Malmström, and F. Powrie, Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation, J Exp Med, vol.192, issue.2, pp.295-302, 2000.

H. Von-boehmer, Mechanisms of suppression by suppressor T cells, Nat Immu nol, vol.6, issue.4, pp.338-382, 2005.

L. Weiss, C. Piketty, L. Assoumou, C. Didier, L. Caccavelli et al., Relationship between regulatory T cells and immune activation in human immunodeficiency virus-infected patients interrupting antiretroviral therapy, PLoS One, vol.5, issue.7, p.11659, 2010.

G. Petitjean, M. F. Chevalier, F. Tibaoui, C. Didier, M. E. Manea et al., Level of double negative T cells, which produce TGF-? and IL-10, predicts CD8 T-cell activation in primary HIV-1 infection, AIDS, vol.26, issue.2, pp.139-187, 2012.
URL : https://hal.archives-ouvertes.fr/pasteur-02006421

M. F. Chevalier, C. Didier, G. Petitjean, M. Karmochkine, P. M. Girard et al., Phenotype alterations in regulatory T-cell subsets in primary HIV infection and identification of Tr1-like cells as the main interleukin 10-producing CD4+ T cells, J Infect Dis, vol.211, issue.5, pp.769-79, 2015.
URL : https://hal.archives-ouvertes.fr/pasteur-02573709

C. Vinton, N. R. Klatt, L. D. Harris, J. A. Briant, . Sanders-beer et al., CD4-like immunological function by CD4-T cells in multiple natural hosts of simian immunodeficiency virus, J Virol, vol.85, issue.17, pp.8702-8710, 2011.

V. Sundaravaradan, R. Saleem, L. Micci, M. A. Gasper, A. M. Ortiz et al., Multifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infection, PLoS Pathog, vol.9, issue.6, p.1003441, 2013.

S. Kalyan and D. Kabelitz, Defining the nature of human ?? T cells: a biographical sketch of the highly empathetic, Cell Mol Immunol, vol.10, issue.1, pp.21-30, 2013.

D. Kabelitz and W. He, The multifunctionality of human V?9V?2 ?? T cells: clonal plasticity or distinct subsets?, Scand J Immunol, vol.76, issue.3, pp.213-235, 2012.

M. Bonneville, R. L. O'brien, and W. K. Born, Gammadelta T cell effector functions: a blend of innate programming and acquired plasticity, Nat Rev Immunol, issue.7, pp.467-78, 2010.

A. Poggi and M. R. Zocchi, ?? T Lymphocytes as a first line of immune defense: old and new ways of antigen recognition and implications for cancer immunotherapy, Front Immunol, vol.5, p.575, 2014.

S. Boullier, M. Cochet, F. Poccia, and M. L. Gougeon, CDR3-independent gamma delta V delta 1+ T cell expansion in the peripheral blood of HIV-infected persons, J Immunol, vol.154, issue.3, pp.1418-1449, 1995.

F. Poccia, S. Boullier, H. Lecoeur, M. Cochet, Y. Poquet et al., Peripheral V gamma 9/V delta 2 T cell deletion and anergy to nonpeptidic mycobacterial antigens in asymptomatic HIV-1-infected persons, J Immunol, vol.157, issue.1, pp.449-61, 1996.

H. Li and C. D. Pauza, HIV envelope-mediated, CCR5/?4?7-dependent killing of CD4-negative ?? T cells which are lost during progression to AIDS, Blood, vol.118, issue.22, pp.5824-5855, 2011.

S. Imlach, C. Leen, J. E. Bell, and P. Simmonds, Phenotypic analysis of peripheral blood gammadelta T lymphocytes and their targeting by human immunodeficiency virus type 1 in vivo, Virology, vol.305, issue.2, pp.415-442, 2003.

N. Soriano-sarabia, N. M. Archin, R. Bateson, N. P. Dahl, A. M. Crooks et al., Peripheral V?9V?2 T cells are a novel reservoir of latent HIV infection, PLoS Pathog, vol.11, issue.10, p.1005201, 2015.

Z. Li, Y. Jiao, Y. Hu, L. Cui, D. Chen et al., Distortion of memory V?2 ?? T cells contributes to immune dysfunction in chronic HIV infection, Cell Mol Immunol, vol.12, issue.5, pp.604-618, 2015.

E. Cimini, C. Agrati, D. 'offizi, G. Vlassi, C. Casetti et al., Primary and chronic HIV infection differently modulates mucosal V?1 and V?2 T-cells differentiation profile and effector functions, PLoS One, vol.10, issue.6, p.129771, 2015.

J. Ye, C. Ma, E. C. Hsueh, C. S. Eickhoff, Y. Zhang et al., Tumorderived ?? regulatory T cells suppress innate and adaptive immunity through the induction of immunosenescence, J Immunol, vol.190, issue.5, pp.2403-2417, 2013.

A. A. Kühl, N. N. Pawlowski, K. Grollich, M. Blessenohl, J. Westermann et al., Human peripheral gammadelta T cells possess regulatory potential, Immunology, vol.128, issue.4, pp.580-588, 2009.

C. Peters, H. H. Oberg, D. Kabelitz, and D. Wesch, Phenotype and regulation of immunosuppressive V?2-expressing ?? T cells, Cell Mol Life Sci, vol.71, issue.10, pp.1943-60, 2014.

J. Zheng, Y. Liu, Y. L. Lau, and W. Tu, ??-T cells: an unpolished sword in human anti-infection immunity, Cell Mol Immunol, vol.10, issue.1, pp.50-57, 2013.

A. Roux, G. Mourin, M. Larsen, S. Fastenackels, A. Urrutia et al., Differential impact of age and cytomegalovirus infection on the ?? T cell compartment, J Immunol, vol.191, issue.3, pp.1300-1306, 2013.
URL : https://hal.archives-ouvertes.fr/hal-02455351

V. Pitard, D. Roumanes, X. Lafarge, L. Couzi, I. Garrigue et al., Longterm expansion of effector/memory Vdelta2-gammadelta T cells is a specific blood signature of CMV infection, Blood, vol.112, issue.4, pp.1317-1341, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00356753

F. Hua, N. Kang, Y. A. Gao, L. X. Cui, D. N. Ba et al., Potential regulatory role of in vitro-expanded V?1 T cells from human peripheral blood, Immunol Res, vol.56, issue.1, pp.172-80, 2013.

S. R. Roff, E. N. Noon-song, and J. K. Yamamoto, The significance of interferon-? in HIV-1 pathogenesis, therapy, and prophylaxis, Front Immunol, vol.4, p.498, 2014.

M. O. Li, Y. Y. Wan, S. Sanjabi, A. K. Robertson, and R. A. Flavell, Transforming growth factor-beta regulation of immune responses, Annu Rev Immunol, vol.24, pp.99-146, 2006.

M. F. Chevalier, G. Petitjean, C. Dunyach-rémy, C. Didier, P. M. Girard et al., The Th17/Treg ratio, IL-1RA and sCD14 levels in primary HIV infection predict the T-cell activation set point in the absence of systemic microbial translocation, PLoS Pathog, vol.9, issue.6, p.1003453, 2013.

M. F. Chevalier, C. Didier, P. M. Girard, M. E. Manea, P. Campa et al., CD4 T-cell responses in primary HIV infection: interrelationship with immune activation and virus burden, Front Immunol, vol.7, p.395, 2016.

M. A. Jenabian, M. El-far, K. Vyboh, I. Kema, C. T. Costiniuk et al., Immunosuppressive tryptophan catabolism and gut mucosal dysfunction following early HIV infection, J Infect Dis, vol.212, issue.3, pp.355-66, 2015.

I. Sereti, S. J. Krebs, N. Phanuphak, J. L. Fletcher, B. Slike et al., Persistent, albeit reduced, chronic inflammation in persons starting antiretroviral therapy in acute HIV infection, Clin Infect Dis, vol.64, issue.2, pp.124-155, 2017.

C. D. Pauza, B. Poonia, H. Li, C. Cairo, and D. Chaudhry, ?? T cells in HIV disease: past, present, and future, Front Immunol, vol.5, p.687, 2014.

A. Mocroft, J. D. Lundgren, M. L. Sabin, A. Monforte, N. Brockmeyer et al., Risk factors and outcomes for late presentation for HIV-positive