Expansion of the SOS regulon of Vibrio cholerae through extensive transcriptome analysis and experimental validation - Archive ouverte HAL Access content directly
Journal Articles BMC Genomics Year : 2018

Expansion of the SOS regulon of Vibrio cholerae through extensive transcriptome analysis and experimental validation

(1) , (1) , (2) , (2) , (2) , (2) , (3) , (3) , (4) , (4) , (4) , (2) , (1)
1
2
3
4

Abstract

The SOS response is an almost ubiquitous response of cells to genotoxic stresses. The full complement of genes in the SOS regulon for Vibrio species has only been addressed through bioinformatic analyses predicting LexA binding box consensus and in vitro validation. Here, we perform whole transcriptome sequencing from Vibrio cholerae treated with mitomycin C as an SOS inducer to characterize the SOS regulon and other pathways affected by this treatment.
Fichier principal
Vignette du fichier
bmc.pdf (1.74 Mo) Télécharger le fichier
Origin : Publication funded by an institution
Loading...

Dates and versions

pasteur-02562431 , version 1 (04-05-2020)

Licence

Attribution - CC BY 4.0

Identifiers

Cite

Evelyne Krin, Sebastian Aguilar Pierlé, Odile Sismeiro, Bernd Jagla, Marie-Agnès Dillies, et al.. Expansion of the SOS regulon of Vibrio cholerae through extensive transcriptome analysis and experimental validation. BMC Genomics, 2018, 19 (1), pp.373. ⟨10.1186/s12864-018-4716-8⟩. ⟨pasteur-02562431⟩
38 View
116 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More