B cell differentiation and isotype switching is related to division cycle number, J. Exp. Med, vol.184, pp.277-281, 1996. ,
VMD: visual molecular dynamics, J. Mol. Graph, vol.14, issue.96, pp.18-23, 1996. ,
Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1, Proc. Natl. Acad. Sci. USA, vol.101, 1975. ,
Regulation of AID, the B-cell genome mutator, Genes Dev, vol.27, pp.1-17, 2013. ,
eEF1A is a novel component of the mammalian nuclear protein export machinery, Mol. Biol. Cell, vol.19, pp.5296-5308, 2008. ,
, The APOBEC3C crystal structure and the interface for HIV-1, 2012.
, Vif binding, Nat. Struct. Mol. Biol, vol.19, pp.1005-1010
Attenuating homologous recombination stimulates an AID-induced antileukemic effect, J. Exp. Med, vol.210, pp.1021-1033, 2013. ,
Endogenous APOBEC3A DNA cytosine deaminase is cytoplasmic and nongenotoxic, J. Biol. Chem, vol.288, pp.17253-17260, 2013. ,
Inhibition of translation by cytotrienin A-a member of the ansamycin family, RNA, vol.16, pp.2404-2413, 2010. ,
Structural basis for the binding of didemnins to human elongation factor eEF1A and rationale for the potent antitumor activity of these marine natural products, J. Med. Chem, vol.47, pp.4439-4452, 2004. ,
eEF1A: thinking outside the ribosome, J. Biol. Chem, vol.285, pp.21209-21213, 2010. ,
Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase, J. Exp. Med, vol.199, pp.1235-1244, 2004. ,
The antiproliferative agent didemnin B uncompetitively inhibits palmitoyl protein thioesterase, Biochemistry, vol.37, pp.10488-10492, 1998. ,
Development and characterization of channel catfish long term B cell lines, J. Immunol, vol.152, pp.2180-2189, 1994. ,
Didemnin B-an immunosuppressive cyclic peptide that stimulates murine hemagglutinating antibody responses and induces leukocytosis in vivo, Transplantation, vol.43, pp.133-139, 1987. ,
Activation induced deaminase: how much and where?, Semin. Immunol, vol.24, pp.246-254, 2012. ,
Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90, J. Exp. Med, vol.207, pp.2751-2765, 2010. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00819549
Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1, EMBO J, vol.31, pp.679-691, 2012. ,
Elongation factors in protein biosynthesis, Trends Biochem. Sci, vol.28, pp.162-164, 2003. ,
Proteasomal degradation restricts the nuclear lifespan of AID, J. Exp. Med, vol.205, pp.1357-1368, 2008. ,
URL : https://hal.archives-ouvertes.fr/inserm-00321674
Activation-induced cytidine deaminase initiates immunoglobulin gene conversion and hypermutation by a common intermediate, E179, vol.2, 2004. ,
APOBEC-1 and AID are nucleo-cytoplasmic trafficking proteins but APOBEC3G cannot traffic, Biochem. Biophys. Res. Commun, vol.350, pp.214-219, 2006. ,
Activation-induced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks, J. Biol. Chem, vol.279, pp.26395-26401, 2004. ,
The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsensemediated decay, EMBO J, vol.22, pp.3971-3982, 2003. ,
GTP-dependent binding of the antiproliferative agent didemnin to elongation factor 1 alpha, J. Biol. Chem, vol.269, pp.15411-15414, 1994. ,
Didemnin binds to the protein palmitoyl thioesterase responsible for infantile neuronal ceroid lipofuscinosis, Proc. Natl. Acad. Sci. USA, vol.93, pp.4316-4319, 1996. ,
Macromolecular modeling with rosetta, Annu. Rev. Biochem, vol.77, pp.363-382, 2008. ,
The role of activation-induced deaminase in lupus nephritis, Autoimmunity, vol.46, pp.115-120, 2013. ,
Evolution of transcriptional enhancers in the immunoglobulin heavy-chain gene: functional characteristics of the zebrafish Emu3? enhancer, Immunogenetics, vol.57, pp.129-139, 2005. ,
The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence, Proc. Natl. Acad. Sci. USA, vol.106, pp.6736-6741, 2009. ,
Cytoplasmic activationinduced cytidine deaminase (AID) exists in stoichiometric complex with translation elongation factor 1? (eEF1A), Proc. Natl. Acad. Sci. USA, vol.108, pp.18366-18371, 2011. ,
of the AID protein in normal and neoplastic B cells, Semin. Immunol, vol.24, pp.3318-3325, 2012. ,
Active nuclear import and cytoplasmic retention of activation-induced deaminase, Nat. Struct. Mol. Biol, vol.16, pp.517-527, 2009. ,
AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization, Proc. Natl. Acad. Sci. USA, vol.99, pp.7003-7008, 2002. ,
AID is required for c-myc/IgH chromosome translocations in vivo, Cell, vol.118, pp.431-438, 2004. ,
Role of genomic instability and p53 in AID-induced c-myc-Igh translocations, Nature, vol.440, pp.105-109, 2006. ,
Activationinduced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2), Cell, vol.102, pp.79-88, 2000. ,
AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations, Mol. Cell, vol.36, pp.631-641, 2009. ,
Altering chemosensitivity by modulating translation elongation, PLoS ONE, vol.4, p.5428, 2009. ,
Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination, Proc. Natl. Acad. Sci. USA, vol.102, pp.13242-13247, 2005. ,
Analysis of reptilian APOBEC1 suggests that RNA editing may not be its ancestral function, Mol. Biol. Evol, vol.28, pp.1125-1129, 2011. ,
Two regions within the aminoterminal half of APOBEC3G cooperate to determine cytoplasmic localization, J. Virol, vol.82, pp.9591-9599, 2008. ,
Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1, Proc. Natl. Acad. Sci. USA, vol.110, pp.1303-1308, 2013. ,
Isolation and characterization of eukaryotic translation initiation, elongation and termination factors, 1996. ,
, , pp.165-176
REG-? associates with and modulates the abundance of nuclear activationinduced deaminase, J. Exp. Med, vol.208, pp.2385-2391, 2011. ,
Combinatorial mechanisms regulating AID-dependent DNA deamination: interacting proteins and posttranslational modifications, Semin. Immunol, vol.24, pp.264-272, 2012. ,
Pathways of chaperone-mediated protein folding in the cytosol, Nat. Rev. Mol. Cell Biol, vol.5, pp.781-791, 2004. ,
Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination, Proc. Natl. Acad. Sci. USA, vol.111, pp.988-997, 2014. ,