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. Saclay, The chemogenomic and Biological Screening Platform of Pasteur is funded by the Global Care initiative and Institut Carnot Pasteur MS. We thank the Faulon Lab and Agou Lab members for fruitful discussions. We thank Claire Donnat (from Stanford University) for the data analysis advice that she kindly gave us. We thank Stephen McGovern (from INRAE) who generously provided purified sfGFP and Bikash Ranjan Semal (from INRAE) for producing