HIV prevention 2020: a framework for delivery and a call for action, Lancet HIV, vol.3, issue.7, pp.323-355, 2016. ,
Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection, Aids, vol.17, issue.13, pp.1871-79, 2003. ,
, DHHS. Panel on antiretroviral guidelines for adults and adolescents
Amplified transmission of HIV-1: comparison of HIV-1 concentrations in semen and blood during acute and chronic infection, Aids, vol.21, issue.13, pp.1723-1753, 2007. ,
HIV in body fluids during primary HIV infection: implications for pathogenesis, treatment and public health, Aids, vol.15, issue.7, pp.837-882, 2001. ,
Brief but efficient: acute HIV infection and the sexual transmission of HIV, J Infect Dis, vol.189, issue.10, pp.1785-92, 2004. ,
Plasma and cervical viral loads among Ugandan and Zimbabwean women during acute and early HIV-1 infection, Aids, vol.24, issue.4, pp.573-82, 2010. ,
The role of acute and early HIV infection in the spread of HIV and implications for transmission prevention strategies in Lilongwe, Malawi: a modelling study, Lancet, vol.378, issue.9787, pp.256-68, 2011. ,
, European AIDS clinical society Brussels, 2017.
, Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents, 2015.
European guideline on HIV testing, Int J STD AIDS, vol.25, issue.10, pp.695-704, 2014. ,
Antiretroviral treatment of adult HIV infection: 2014 recommendations of the international antiviral society-USA panel, 2013. ,
, Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach, 2016.
, Consolidated guidelines on HIV testing services, 2015.
Effectiveness and safety of oral HIV preexposure prophylaxis for all populations, Aids, vol.30, issue.12, pp.1973-83, 2016. ,
The size of the expressed HIV reservoir predicts timing of viral rebound after treatment interruption, Aids, vol.30, issue.3, pp.343-53, 2016. ,
How does the timing of antiretroviral therapy initiation in acute infection affect HIV reservoirs?, Curr Opin HIV AIDS, vol.10, issue.1, pp.18-28, 2015. ,
Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection, PNAS, vol.109, issue.24, pp.9523-9551, 2012. ,
Immune activation during acute HIV infection and the impact of early antiretroviral therapy, Curr Opin HIV AIDS, vol.11, issue.2, pp.163-72, 2016. ,
Determinants of HIV-1 transmission in men who have sex with men: a combined clinical, epidemiological and phylogenetic approach, Aids, vol.24, issue.11, pp.1739-1786, 2010. ,
Costs per diagnosis of acute HIV infection in community-based screening strategies: a comparative analysis of four screening algorithms, Clin Infect Dis, vol.62, issue.4, pp.501-512, 2016. ,
Ten years of screening and testing for acute HIV infection in North Carolina, J Acquir Immune Defic Syndr, vol.71, issue.1, pp.111-130, 2016. ,
How many HIV infections may be averted by targeting primary infection in men who have sex with men? Quantification of changes in transmission-risk behavior, using an individualbased model, J Infect Dis, vol.210, issue.2, pp.594-603, 2014. ,
Implementing early diagnosis and treatment: programmatic considerations, Curr Opin HIV AIDS, vol.10, issue.1, pp.69-75, 2015. ,
Programmatic implications of acute and early HIV infection, J Infect Dis, vol.212, issue.9, pp.1351-60, 2015. ,
Scoping studies: towards a methodological framework, Int J Soc Res Methodol, vol.8, issue.1, pp.19-32, 2005. ,
Studying the organisation and delivery of health services: research methods, pp.188-220, 2001. ,
HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck, Science, vol.345, issue.6193, p.1254031, 2014. ,
Feasibility of pooling sera for HIV-1 viral RNA to diagnose acute primary HIV-1 infection and estimate HIV incidence, Aids, vol.14, issue.17, pp.2751-57, 2000. ,
Prospective study of acute HIV-1 infection in adults in East Africa and Thailand, N Engl J Med, vol.374, pp.2120-2150, 2016. ,
Control of sexually transmitted diseases for AIDS prevention in Uganda: a randomised community trial. Rakai Project Study Group, Lancet, vol.353, issue.9152, pp.525-560, 1999. ,
, Journal of the International AIDS Society, vol.20, 2017.
Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, J Infect Dis, vol.191, issue.9, pp.1403-1412, 2005. ,
HIV-1 transmission, by stage of infection, J Infect Dis, vol.198, issue.5, pp.687-93, 2008. ,
Reassessment of HIV-1 acute phase infectivity: accounting for heterogeneity and study design with simulated cohorts, Plos Med, vol.12, issue.3, p.1001801, 2015. ,
Transmission networks of HIV-1 among men having sex with men in the Netherlands, Aids, vol.24, issue.2, pp.271-82, 2010. ,
Phylogenetic analysis consistent with a clinical history of sexual transmission of HIV-1 from a single donor reveals transmission of highly distinct variants, Retrovirology, vol.8, p.54, 2011. ,
High Transmissibility During early HIV infection among men who have sex with men, J Infect Dis, vol.211, issue.11, pp.1757-60, 2015. ,
Molecular epidemiology reveals long-term changes in HIV type 1 subtype B transmission in Switzerland, J Infect Dis, vol.201, issue.10, pp.1488-97, 2010. ,
Transmission of HIV-1 during primary infection: relationship to sexual risk and sexually transmitted infections, Aids, vol.19, issue.1, pp.85-90, 2005. ,
Transmission clustering drives the onward spread of the HIV epidemic among men who have sex with men in Quebec, J Infect Dis, vol.204, issue.7, pp.1115-1134, 2011. ,
Phylogenetic reconstruction of transmission events from individuals with acute HIV infection: toward more-rigorous epidemiological definitions, J Infect Dis, vol.199, issue.3, pp.427-458, 2009. ,
HIV transmissions during seroconversion contribute significantly to new infections in men who have sex with men in Australia, AIDS Res Hum Retroviruses, vol.28, issue.5, pp.460-64, 2012. ,
Recent HIV-1 infection contributes to the viral diffusion over the French territory with a recent increasing frequency, Plos One, vol.7, issue.2, p.31695, 2012. ,
High rates of forward transmission events after acute/early HIV-1 infection, J Infect Dis, vol.195, issue.7, pp.951-59, 2007. ,
Sources of HIV infection among men having sex with men and implications for prevention, Sci Transl Med, vol.8, issue.320, pp.320-322, 2016. ,
Phylogenetic studies of transmission dynamics in generalized HIV epidemics: an essential tool where the burden is greatest?, J Acquir Immune Defic Syndr, vol.67, issue.2, pp.181-95, 2014. ,
Role of acute and early HIV infection in the sexual transmission of HIV, Curr Opin HIV AIDS, vol.5, issue.4, pp.277-82, 2010. ,
How many sexually-acquired HIV infections in the USA are due to acute-phase HIV transmission?, Aids, vol.21, issue.12, pp.1625-1654, 2007. ,
Sexually acquired HIV infections in the USA due to acute-phase HIV transmission: an update, Aids, vol.23, issue.13, pp.1792-94, 2009. ,
Primary HIV infection as source of HIV transmission within steady and casual partnerships among homosexual men, Aids, vol.18, issue.9, pp.1311-1331, 2004. ,
Acute HIV-1 infection, N Engl J Med, vol.364, issue.20, pp.1943-54, 2011. ,
HIV-1 transmission during early infection in men who have sex with men: a phylodynamic analysis, Plos Med, vol.10, issue.12, p.1001568, 2013. ,
No HIV stage is dominant in driving the HIV epidemic in sub-Saharan Africa, Aids, vol.22, issue.9, pp.1055-61, 2008. ,
Role of acute infection in HIV transmission, Lancet, vol.378, issue.9807, 1913. ,
, , 2016.
, SEARCH. Clinicaltrials.gov, 2016.
Field evaluation of the Abbott ARCHITECT HIV Ag/Ab Combo immunoassay, J Clin Virol, vol.58, issue.1, pp.70-75, 2013. ,
Acute HIV infection and implications of fourth-generation HIV screening in emergency departments, Ann Emerg Med, vol.64, issue.5, pp.547-51, 2014. ,
Rapid HIV screening: missed opportunities for HIV diagnosis and prevention, J Clin Virol, vol.54, issue.1, pp.42-47, 2012. ,
Performance of the fourth-generation Bio-Rad GS HIV Combo Ag/ Ab enzyme immunoassay for diagnosis of HIV infection in Southern Africa, J Clin Virol, vol.62, pp.75-79, 2015. ,
Identification of acute HIV infection using fourth-generation testing in an opt-out emergency department screening program, Ann Emerg Med, vol.64, issue.5, pp.537-583, 2014. ,
Could the new HIV combined p24 antigen and antibody assays replace p24 antigen specific assays?, J Virol Methods, vol.143, issue.1, pp.86-94, 2007. ,
Screening yield of HIV antigen/antibody combination and pooled HIV RNA testing for acute HIV infection in a high-prevalence population, Jama, vol.315, issue.7, pp.682-90, 2016. ,
Ten years of HIV testing with fourth generation assays: the Amsterdam experience, J Clin Virol, vol.52, issue.1, pp.67-76, 2011. ,
, Laboratory testing for the diagnosis of HIV infection: updated recommendations, Centers for Disease Control and Prevention (CDC)
Impact of nucleic acid testing relative to antigen/antibody combination immunoassay on the detection of acute HIV infection, Aids, vol.29, pp.793-800, 2015. ,
Pooled nucleic acid testing increases the diagnostic yield of acute HIV infections in a high-risk population compared to 3rd and 4th generation HIV enzyme immunoassays, J Clin Virol, vol.61, issue.1, pp.132-169, 2014. ,
Initiation of antiretroviral therapy during acute HIV-1 infection leads to a high rate of nonreactive HIV serology, Clin Infect Dis, vol.63, pp.555-61, 2016. ,
, , 2016.
Performance of an alternative HIV diagnostic algorithm using the ARCHITECT HIV Ag/Ab Combo assay and potential utility of sample-tocutoff ratio to discriminate primary from established infection, J Clin Virol, vol.58, issue.1, pp.38-43, 2013. ,
Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana, N Engl J Med, vol.367, issue.5, pp.423-457, 2012. ,
Antiretroviral prophylaxis for HIV prevention in heterosexual men and women, N Engl J Med, vol.367, issue.5, pp.399-410, 2012. ,
Preexposure chemoprophylaxis for HIV prevention in men who have sex with men, N Engl J Med, vol.363, issue.27, pp.2587-99, 2010. ,
Preexposure prophylaxis for HIV infection among African women, N Engl J Med, vol.367, issue.5, pp.411-433, 2012. ,
Screening for acute HIV infection in South Africa: finding acute and chronic disease, HIV Med, vol.12, issue.1, pp.46-53, 2011. ,
Acute HIV-1 infection is highly prevalent in Ugandan adults with suspected malaria, Aids, vol.24, issue.12, pp.1945-52, 2010. ,
, Journal of the International AIDS Society, vol.20, 2017.
Rapid, real-time detection of acute HIV infection in patients in Africa, J Infect Dis, vol.195, issue.3, pp.416-440, 2007. ,
Should South Africa be performing nucleic acid testing on HIV enzyme-linked immunosorbent assaynegative samples?, J Clin Microbiol, vol.48, issue.9, pp.3407-3416, 2010. ,
Screening for acute HIV infections and estimating HIV incidence among female sex workers from low-grade venues in Guangxi, China, PLoS One, vol.9, issue.6, p.99522, 2014. ,
Challenges of diagnosing acute HIV-1 subtype C infection in African women: performance of a clinical algorithm and the need for pointof-care nucleic-acid based testing, PLoS One, vol.8, issue.4, p.62928, 2013. ,
Frequent detection of acute primary HIV infection in men in Malawi, Aids, vol.18, issue.3, pp.517-541, 2004. ,
Incorporating acute HIV screening into routine HIV testing at sexually transmitted infection clinics, and HIV testing and counseling centers in Lilongwe, Malawi, J Acquir Immune Defic Syndr, vol.71, issue.3, pp.272-80, 2016. ,
High prevalence of symptomatic acute HIV infection in an outpatient ward in southern Mozambique: identification and follow-up, Aids, vol.24, issue.4, pp.603-611, 2010. ,
Costeffectiveness of a fourth-generation combination immunoassay for human immunodeficiency virus (HIV) antibody and p24 antigen for the detection of HIV infections in the USA, HIV Clin Trials, vol.13, issue.1, pp.11-22, 2012. ,
The costeffectiveness of symptom-based testing and routine screening for acute HIV infection in men who have sex with men in the USA, Aids, vol.25, issue.14, pp.1779-87, 2011. ,
Cost savings associated with testing of antibodies, antigens, and nucleic acids for diagnosis of acute HIV infection, J Clin Microbiol, vol.50, issue.6, pp.1874-78, 2012. ,
Screening for acute HIV infection in community-based settings: cost-effectiveness and impact on transmissions, J Infect, vol.73, pp.476-84, 2016. ,
Detection of acute infections during HIV testing in North Carolina, N Engl J Med, vol.352, issue.18, pp.1873-83, 2005. ,
Detection of acute HIV infections, N Engl J Med, vol.353, issue.6, pp.631-664, 2005. ,
Cost-effectiveness of pooled nucleic acid amplification testing for acute HIV infection after third-generation HIV antibody screening and rapid testing in the USA: a comparison of three public health settings, Plos Med, vol.7, issue.9, p.1000342, 2010. ,
Detection of acute HIV-1 infections utilizing NAAT technology in, J Clin Virol, vol.58, issue.1, pp.48-53, 2013. ,
, Geneva: WHO, Prequalification of In Vitro Diagnostics: PUBLIC REPORT (Alere? HIV Combo), 2016.
Evaluation of a rapid point of care test for detecting acute and established HIV infection, and examining the role of study quality on diagnostic accuracy: a bayesian meta-analysis, Plos One, vol.11, issue.2, p.149592, 2016. ,
Multi-centre evaluation of the determine HIV combo assay when used for point of care testing in a high risk clinic-based population, Plos One, vol.9, issue.4, p.94062, 2014. ,
Poor performance of the determine HIV-1/2 Ag/Ab combo fourthgeneration rapid test for detection of acute infections in a national household survey in Swaziland, J Clin Microbiol, vol.52, issue.10, pp.3743-3791, 2014. ,
Detection of acute HIV infection: a field evaluation of the determine(R) ,
, Ag/Ab combo test, J Infect Dis, vol.205, issue.4, pp.528-562, 2012.
Clinical evaluation of the Determine HIV-1/2 Ag/Ab Combo test, J Infect Dis, vol.206, issue.12, pp.1947-1996, 2012. ,
Field accuracy of fourth-generation rapid diagnostic tests for acute HIV-1: a systematic review, Aids, vol.29, issue.18, pp.2465-71, 2015. ,
Diagnosing acute HIV infection at point of care: a retrospective analysis of the sensitivity and specificity of a fourth-generation point-of-care test for detection of HIV core protein p24, Sex Transm Infect, vol.93, issue.2, pp.100-101, 2017. ,
Performance of the bio-rad geenius HIV1/2 supplemental assay in detecting 'recent' HIV infection and calculating population incidence, J Acquir Immune Defic Syndr, vol.73, pp.581-88, 2016. ,
Accurate early infant HIV diagnosis in primary health clinics using a point-ofcare nucleic acid test, J Acquir Immune Defic Syndr, vol.67, issue.1, pp.1-4, 2014. ,
, Prequalification of in vitro diagnostics: PUBLIC REPORT (Alere? q HIV-1/2 Detect), 2016.
SAMBA HIV semiquantitative test, a new point-of-care viral-load-monitoring assay for resource-limited settings, J Clin Microbiol, vol.52, issue.9, pp.3377-83, 2014. ,
Laboratory evaluation of the liat HIV quant (IQuum) whole blood and plasma HIV-1 viral load assays for point-of-care testing in South Africa, J Clin Microbiol, vol.53, pp.1616-1637, 2015. ,
Diagnostic accuracy of the point-of-care xpert HIV-1 viral load assay in a South African HIV clinic, J Acquir Immune Defic Syndr, vol.72, issue.2, pp.45-53, 2016. ,
Evaluation of xpert HIV-1 qual assay for resolution of HIV-1 infection in samples with negative or indeterminate geenius HIV-1/2 results, J Clin Virol, vol.76, pp.1-3, 2016. ,
Signs or symptoms of acute HIV infection in a cohort undergoing community-based screening, Emerg Infect Dis, vol.22, issue.3, pp.532-566, 2016. ,
Most adults seek urgent healthcare when acquiring HIV-1 and are frequently treated for malaria in coastal Kenya, Aids, vol.25, issue.9, pp.1219-1243, 2011. ,
Missed opportunities for diagnosing primary HIV infection, Sex Transm Infect, vol.84, issue.1, pp.14-16, 2008. ,
Acute HIV-1 infection in sub-Saharan Africa: a common occurrence overlooked, Aids, vol.28, issue.9, pp.1365-67, 2014. ,
Diagnosing acute and prevalent HIV-1 infection in young African adults seeking care for fever: a systematic review and audit of current practice, Int Health, vol.6, issue.2, pp.82-92, 2014. ,
Acute HIV-1 infection is as common as malaria in young febrile adults seeking care in coastal Kenya, Aids, vol.28, issue.9, pp.1357-63, 2014. ,
Viral dynamics in primary HIV-1 infection. Karolinska Institutet Primary HIV Infection Study Group, Aids, vol.14, issue.15, pp.2283-91, 2000. ,
Virus load during primary human immunodeficiency virus (HIV) type 1 infection is related to the severity of acute HIV illness in Kenyan women, Clin Infect Dis, vol.35, issue.1, pp.77-81, 2002. ,
Outcomes of AHI screening and immediate ART initiation in Coastal Kenya, 2017. ,
Higher set point plasma viral load and more-severe acute HIV type 1 (HIV-1) illness predict mortality among high-risk HIV-1-infected African women, Clin Infect Dis, vol.42, issue.9, pp.1333-1372, 2006. ,
Targeted screening of at-risk adults for acute HIV-1 infection in sub-Saharan Africa, Aids, vol.29, issue.3, pp.221-251, 2015. ,
Improved detection of acute HIV-1 infection in sub-Saharan Africa: development of a risk score algorithm, Aids, vol.21, issue.16, pp.2237-2279, 2007. ,
Evaluation of an empiric risk screening score to identify acute and early HIV-1 infection among MSM in Coastal Kenya, Aids, vol.27, issue.13, pp.2163-66, 2013. ,
, Journal of the International AIDS Society, vol.20, 2017.
No treatment versus 24 or 60 weeks of antiretroviral treatment during primary HIV infection: the randomized Primo-SHM trial, PLoS Med, vol.9, issue.3, p.1001196, 2012. ,
Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study, PLoS Pathog, vol.9, issue.3, p.1003211, 2013. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01420534
Shortcourse antiretroviral therapy in primary HIV infection, N Engl J Med, vol.368, issue.3, pp.207-224, 2013. ,
The immune response during acute HIV-1 infection: clues for vaccine development, Nat Rev Immunol, vol.10, issue.1, pp.11-23, 2010. ,
Longterm antiretroviral treatment initiated at primary HIV-1 infection affects the size, composition, and decay kinetics of the reservoir of HIV-1-infected CD4 T cells, J Virol, vol.88, issue.17, pp.10056-65, 2014. ,
Combined ART started during acute HIV infection protects central memory CD4+ T cells and can induce remission, J Antimicrob Chemother, vol.70, issue.7, pp.2108-2128, 2015. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01420415
Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1, J Infect Dis, vol.191, issue.9, pp.1410-1428, 2005. ,
Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection, PLoS One, vol.7, issue.3, p.33948, 2012. ,
Impact of the timing of initiation of antiretroviral therapy during primary HIV-1 infection on the decay of cell-associated HIV-DNA, Clin Infect Dis, vol.60, issue.11, pp.1715-1736, 2015. ,
Defective proviruses rapidly accumulate during acute HIV-1 infection, Nat Med, vol.22, pp.1043-1092, 2016. ,
The effect of timing of antiretroviral therapy on CD4(+) T-cell reconstitution in the intestine of HIV-infected patients, Mucosal Immunol, vol.9, issue.1, pp.265-74, 2016. ,
Immunosuppressive tryptophan catabolism and gut mucosal dysfunction following early HIV infection, J Infect Dis, vol.212, issue.3, pp.355-66, 2015. ,
HIV DNA set point is rapidly established in acute HIV infection and dramatically reduced by early ART, EBioMedicine, vol.11, pp.68-72, 2016. ,
HIV-1 DNA decay dynamics in blood during more than a decade of suppressive antiretroviral therapy, Clin Infect Dis, vol.59, issue.9, pp.1312-1333, 2014. ,
HIV DNA subspecies persist in both activated and resting memory CD4+ T cells during antiretroviral therapy, J Virol, vol.88, issue.6, pp.3516-3542, 2014. ,
Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption, Proc Natl Acad Sci, vol.112, issue.10, pp.1126-1160, 2015. ,
Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size, J Infect Dis, vol.208, issue.8, pp.1202-1213, 2013. ,
Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy, N Engl J Med, vol.368, issue.3, pp.218-248, 2013. ,
Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation, PLoS Pathog, vol.10, issue.12, p.1004543, 2014. ,
Impact of early initiation of antiretroviral therapy in patients with acute HIV infection in, PLoS One, vol.11, issue.4, p.152910, 2016. ,
Multiparametric bioinformatics distinguish the CD4/CD8 ratio as a suitable laboratory predictor of combined T cell pathogenesis in HIV infection, J Immunol, vol.192, issue.5, pp.2099-108, 2014. ,
CD4 cell count and the risk of AIDS or death in HIV-infected adults on combination antiretroviral therapy with a suppressed viral load: a longitudinal cohort study from COHERE, PLoS Med, vol.9, issue.3, p.1001194, 2012. ,
CD4/CD8 ratio normalisation and non-AIDS-related events in individuals with HIV who achieve viral load suppression with antiretroviral therapy: an observational cohort study, Lancet HIV, vol.2, issue.3, pp.98-106, 2015. ,
Early initiation rather than prolonged duration of antiretroviral therapy in HIV infection contributes to the normalization of CD8 T-cell counts, Clin Infect Dis, vol.62, issue.2, pp.250-57, 2016. ,
Enhanced normalisation of CD4/CD8 ratio with early antiretroviral therapy in primary HIV infection, J Int AIDS Soc, vol.17, p.19480, 2014. ,
Long-term antiretroviral therapy initiated during primary HIV-1 infection is key to achieving both low HIV reservoirs and normal T cell counts, J Antimicrob Chemother, vol.68, issue.5, pp.1169-78, 2013. ,
Virological and immunological characteristics of HIVinfected individuals at the earliest stage of infection, J Virus Erad, vol.2, pp.43-48, 2016. ,
CD4/CD8 cell ratio in acute HIV infection and the impact of early antiretroviral therapy, Clin Infect Dis, vol.63, pp.425-451, 2016. ,
Intensive five-drug antiretroviral therapy regimen versus standard triple-drug therapy during primary HIV-1 infection (OPTIPRIM-ANRS 147): a randomised, open-label, phase 3 trial, Lancet Infect Dis, vol.15, issue.4, pp.387-96, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01968121
A randomized open-label study of 3-versus 5-drug combination antiretroviral therapy in newly HIV-1-infected individuals, J Acquir Immune Defic Syndr, vol.66, issue.2, pp.140-187, 2014. ,
Treatment outcome in HIV+ patients receiving 3-or 4-drug regimens during PHI, J Int AIDS Soc, vol.17, 2014. ,
Markers of HIV reservoir size and immune activation after treatment in acute HIV infection with and without raltegravir and maraviroc intensification, J Virus Erad, vol.1, issue.2, pp.116-138, 2015. ,
Anogenital HIV RNA in Thai men who have sex with men in Bangkok during acute HIV infection and after randomization to standard vs. intensified antiretroviral regimens, J Int AIDS Soc, vol.18, p.19470, 2015. ,
Dolutegravir in antiretroviral-naive adults with HIV-1: 96-week results from a randomized dose-ranging study, Aids, vol.27, issue.11, pp.1771-78, 2013. ,
Once-daily dolutegravir versus darunavir plus ritonavir for treatmentnaive adults with HIV-1 infection (FLAMINGO): 96 week results from a randomised, open-label, phase 3b study, Lancet HIV, vol.2, issue.4, pp.127-163, 2015. ,
Detection of acute HIV infections in high-risk patients in California, J Acquir Immune Defic Syndr, vol.42, issue.1, pp.75-79, 2006. ,
Detecting acute human immunodeficiency virus infection using 3 different screening immunoassays and nucleic acid amplification testing for human immunodeficiency virus RNA, Arch Intern Med, vol.170, issue.1, pp.66-74, 2006. ,
Detection of acute HIV infections in an urban HIV counseling and testing population in the USA, J Acquir Immune Defic Syndr, vol.44, issue.2, pp.196-202, 2007. ,
Targeted screening for primary HIV infection through pooled HIV-RNA testing in men who have sex with men, Aids, vol.19, issue.12, pp.1323-1348, 2005. ,
High prevalence of undetected, acute HIV infection in a South Rutstein SE et al, Journal of the International AIDS Society, vol.20, 2017. ,
, Abstract presented at: Third IAS Conference on HIV Pathogenesis and Treatment, 2005.
Botswana's progress toward achieving the 2020 UNAIDS 90-90-90 antiretroviral therapy and virological suppression goals: a population-based survey, Lancet HIV, vol.3, issue.5, pp.221-251, 2016. ,
, UNAIDS. UNAIDS fact sheet, 2016.
Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study, Lancet HIV, vol.3, issue.8, pp.361-87, 2015. ,
HIV-1 drug resistance in the iPrEx preexposure prophylaxis trial, J Infect Dis, vol.210, issue.8, pp.1217-1244, 2014. ,
Preexposure prophylaxis-selected drug resistance decays rapidly after drug cessation, Aids, vol.30, issue.1, pp.31-35, 2016. ,
HIV partner notification is effective and feasible in sub-Saharan Africa: opportunities for HIV treatment and prevention, J Acquir Immune Defic Syndr, vol.56, issue.5, pp.437-479, 2011. ,
Scale-up and case-finding effectiveness of an HIV partner services program in Cameroon: an innovative HIV prevention intervention for developing countries, Sex Transm Dis, vol.40, issue.12, pp.909-923, 2013. ,
Cost-effectiveness of provider-based HIV partner notification in urban Malawi, Health Policy Plan, vol.29, issue.1, pp.115-141, 2014. ,
Assisted partner notification services to augment HIV testing and linkage to care in Kenya: study protocol for a cluster randomized trial, Implement Sci, vol.10, p.23, 2015. ,
Effectiveness of partner services for HIV in Kenya: a cluster randomized trial. Abstract presented at: CROI, 2016. ,
Recruiting male partners for couple HIV testing and counselling in Malawi's option B+ programme: an unblinded randomised controlled trial, Lancet HIV, vol.2, issue.11, pp.483-91, 2015. ,
Number of named partners and number of partners newly diagnosed with HIV infection identified by persons with acute versus established HIV infection, J Acquir Immune Defic Syndr, vol.52, issue.4, pp.509-522, 2009. ,
Sexual behavior during acute HIV infection among men who have sex with men, J Infect Dis, vol.213, issue.12, pp.2020-2041, 2016. ,
Future of phylogeny in HIV prevention, J Acquir Immune Defic Syndr, vol.63, issue.2, pp.248-54, 2013. ,
Ongoing HIV transmission and the HIV care continuum in North Carolina, Plos One, vol.10, issue.6, p.127950, 2015. ,
HPTN 062: a feasibility and acceptability pilot intervention to reduce HIV transmission risk behaviors among individuals with acute and early HIV infection in Lilongwe, AIDS Behav, vol.18, issue.9, pp.1785-800, 2014. ,
HPTN 062: a pilot randomized controlled trial exploring the effect of a motivational-interviewing intervention on sexual behavior among individuals with acute HIV infection in Lilongwe, Plos One, vol.10, issue.5, p.124452, 2015. ,
Sexual activity without condoms and risk of HIV transmission in serodifferent couples when the HIV-positive partner is using suppressive antiretroviral therapy, Jama, vol.316, issue.2, pp.171-81, 2016. ,
Influence of suspected source of infection on disclosure among people with acute HIV in Malawi, IAS, 2015. ,
,
Behavior change following diagnosis with acute/early HIV infectiona move to serosorting with other HIV-infected individuals. The NIMH multisite acute HIV infection study: III, AIDS Behav, vol.13, issue.6, pp.1054-60, 2009. ,
Psychiatric context of acute/early HIV infection. The NIMH multisite acute HIV infection study: IV, AIDS Behav, vol.13, issue.6, pp.1061-67, 2009. ,
Diagnosis and management of acute HIV infection, Infect Dis Clin North Am, vol.21, issue.1, pp.19-48, 2007. ,
Lessons learned about behavioral science and acute/early HIV infection. The NIMH MULTISITE ACUTE HIV infection study: V, AIDS Behav, vol.13, issue.6, pp.1068-74, 2009. ,
Continued high risk sexual behavior following diagnosis with acute HIV infection in South Africa and Malawi: implications for prevention, AIDS Behav, vol.15, issue.6, pp.1243-50, 2011. ,
Incident sexually transmitted infection as a biomarker for high-risk sexual behavior after diagnosis of acute HIV, Sex Transm Dis, vol.41, issue.7, pp.447-52, 2014. ,
Abstract presented at: Pilot study of immediate antiretrovirals and behavioral intervention for persons with acute HIV infection: opportunity for interrupting transmission, 2015. ,
,
The effect of same-day observed initiation of antiretroviral therapy on HIV viral load and treatment outcomes in a U.S. public health setting, J Acquir Immune Defic Syndr, vol.74, issue.1, pp.44-51, 2017. ,
Virologic failure is uncommon after treatment initiation during acute HIV infection, Aids, vol.30, pp.1943-50, 2016. ,
Longitudinal analysis of clinical markers following antiretroviral therapy initiated during acute or early HIV type 1 infection, Clin Infect Dis, vol.42, issue.7, pp.1024-1055, 2006. ,
Overcoming the challenge of diagnosis of early HIV infection: a stepping stone to optimal patient management, Expert Rev Anti Infect Ther, vol.13, issue.10, pp.1189-93, 2015. ,
Effect of text message, phone call, and in-person appointment reminders on uptake of repeat HIV testing among outpatients screened for acute HIV infection in Kenya: a randomized controlled trial, PLoS One, vol.11, issue.4, p.153612, 2016. ,
HIV treatment as prevention: debate and commentary-will early infection compromise treatment-as-prevention strategies, PLoS Med, vol.9, issue.7, p.1001232, 2012. ,
Lessons from acute HIV infection, Curr Opin HIV AIDS, vol.11, pp.555-60, 2016. ,
Heterogeneity of HIV controllers, Models of protection against HIV/SIV, pp.233-52, 2012. ,
Epidemiology and clinical characteristics of elite controllers, Curr Opin HIV AIDS, vol.6, issue.3, pp.163-68, 2011. ,
Estrogen blocks HIV re-emergence from latency and points to gender-specific differences in HIV reservoirs ,
,
Duration of HIV-1 viral suppression on cessation of antiretroviral therapy in primary infection correlates with time on therapy, PLoS One, vol.8, issue.10, p.78287, 2013. ,
Sex-based differences in HIV reservoir activity and residual immune activation. Abstract presented at: CROI, pp.13-16, 2017. ,
,
, Journal of the International AIDS Society, vol.20, 2017.