Salmonella enterica Serovar Panama, an Understudied Serovar Responsible for Extraintestinal Salmonellosis Worldwide

Caisey V Pulford (1) , Blanca M Perez-Sepulveda (1) , Ella V Rodwell (1) , François-Xavier Weill (2) , Kate S Baker (1) , Jay C D Hinton (1)

1 University of Liverpool
2 CNR-ESS - Centre National de Référence - National Reference Center Escherichia coli, Shigella et Salmonella

In recent years nontyphoidal Salmonella has emerged as one of the pathogens most frequently isolated from the bloodstream in humans. Only a small group of Salmonella serovars cause this systemic infection, known as invasive nonty-phoidal salmonellosis. Here, we present a focused minireview on Salmonella enterica serovar Panama, a serovar responsible for invasive salmonellosis worldwide. S. Pan-ama has been linked with infection of extraintestinal sites in humans, causing septi-cemia, meningitis, and osteomyelitis. The clinical picture is often complicated by antimicrobial resistance and has been associated with a large repertoire of transmission vehicles, including human feces and breast milk. Nonhuman sources of S. Pan-ama involve reptiles and environmental reservoirs, as well as food animals, such as pigs. The tendency of S. Panama to cause invasive disease may be linked to certain serovar-specific genetic factors.

Keywords: invasive nontyphoidal Salmonella; Salmonella; Salmonella enterica serovar Panama

Domains: Life Sciences [q-bio]; Microbiology and Parasitology; Bacteriology

Caisey V Pulford, Blanca M Perez-Sepulveda, Ella V Rodwell, François-Xavier Weill, Kate S Baker, et al.. Salmonella enterica Serovar Panama, an Understudied Serovar Responsible for Extraintestinal Salmonellosis Worldwide. Infection and Immunity, 2019, 87 (9), pp.e00273-19. ⟨10.1128/IAI.00273-19⟩. ⟨pasteur-02481860⟩