Eliminating maternal and neonatal tetanus and closing the immunity gap, Lancet, vol.389, pp.1380-1381, 2017. ,
The complete nucleotide sequence of tetanus toxin, Nucleic. Acids Res, vol.14, pp.7809-7812, 1986. ,
Tetanus toxin: primary structure, expression in E. coli, and homology with botulinum toxins, EMBO J, vol.5, pp.2495-2502, 1986. ,
The structural gene for tetanus neurotoxin is on a plasmid, Science, vol.224, pp.881-884, 1984. ,
Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc, EMBO J, vol.11, pp.3577-3583, 1992. ,
Botulinum neurotoxins are zinc proteins, J. Biol. Chem, vol.267, pp.23479-23483, 1992. ,
Tetanus toxin entry. Nidogens are therapeutic targets for the prevention of tetanus, Science, vol.346, pp.1118-1123, 2014. ,
The travel diaries of tetanus and botulinum neurotoxins, Toxicon, vol.147, pp.58-67, 2018. ,
, Tetanus vaccines: WHO position paper, Wkly Epidemiol Rec, vol.92, pp.53-76, 2017.
The genome sequence of Clostridium tetani, the causative agent of tetanus disease, Proc. Ntl. Acad. Sci. (USA), vol.100, pp.1316-1321, 2003. ,
Genome of a chronic osteitis-causing Clostridium tetani, New Microbes New Infect, vol.2, pp.25-26, 2014. ,
Comparative pathogenomics of Clostridium tetani, PLoS One, vol.12, p.182909, 2017. ,
, Genomics of Clostridium tetani. Res Microbiol, vol.166, pp.326-331, 2015.
tetR is a positive regulator of the Tetanus toxin gene in Clostridium tetani and is homologous to botR, Infect. Immun, vol.66, pp.5698-5702, 1998. ,
A proposed nomenclature for cell wall proteins of Clostridium difficile, J Med Microbiol, vol.60, pp.1225-1228, 2011. ,
Identification and characterization of the surface-layer protein of Clostridium tetani, FEMS Microbiol Lett, vol.274, pp.126-131, 2007. ,
The structure of the tetanus toxin reveals pH-mediated domain dynamics, EMBO Rep, vol.18, pp.1306-1317, 2017. ,
Molecular genetics of clostridial neurotoxins, Curr. Top. Microbiol. Immunol, vol.195, pp.161-194, 1995. ,
Tetanus and Botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin, Nature, vol.359, pp.832-835, 1992. ,
Genomic insights into the evolution and ecology of botulinum neurotoxins, Pathog Dis, vol.76, issue.4, p.4978416, 2018. ,
Insights into the evolutionary origins of clostridial neurotoxins from analysis of the Clostridium botulinum strain A neurotoxin gene cluster, BMC Evol Biol, vol.8, p.316, 2008. ,
Genetic characteristics of toxigenic Clostridia and toxin gene evolution, Toxicon, vol.75, pp.63-89, 2013. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01793259
Toxic and nontoxic components of botulinum neurotoxin complex are evolved from a common ancestral zinc protein, Biochem Biophys Res Commun, vol.419, pp.500-504, 2012. ,
Botulinum neurotoxin is shielded by NTNHA in an interlocked complex, Science, vol.335, pp.977-981, 2012. ,
, The Comprehensive Sourcebook of Bacterial Protein Toxins, vol.11, pp.287-336, 2015.
Assembly and function of the botulinum neurotoxin progenitor complex, Curr Top Microbiol Immunol, vol.364, pp.21-44, 2013. ,
Historical Perspectives and Guidelines for Botulinum Neurotoxin Subtype Nomenclature, Toxins (Basel), vol.9, p.38, 2017. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01821691
Discovery of novel bacterial toxins by genomics and computational biology, Toxicon, vol.147, pp.2-12, 2018. ,
Two Feet on the Membrane: Uptake of Clostridial Neurotoxins, Curr Top Microbiol Immunol, vol.406, pp.1-37, 2017. ,
Botulinum neurotoxin homologs in non-Clostridium species, FEBS Lett, vol.589, pp.342-348, 2015. ,
Neurotoxins: Still a Privilege of Clostridia?, Cell Host Microbe, vol.23, pp.145-146, 2018. ,
Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium, Cell Host Microbe, vol.23, pp.169-176, 2018. ,
Three classes of plasmid (47-63 kb) carry the type B neurotoxin gene cluster of group II Clostridium botulinum, Genome Biol Evol, vol.6, pp.2076-2087, 2014. ,
Evidence that plasmid-borne botulinum neurotoxin type B genes are widespread among Clostridium botulinum serotype B strains, PLoS One, vol.4, p.4829, 2009. ,
Botulinum neurotoxin-encoding plasmids can be conjugatively transferred to diverse clostridial strains, Sci Rep, vol.8, p.3100, 2018. ,
Macrophage responses to bacterial toxins: a balance between activation and suppression, Immunol Res, vol.50, pp.118-123, 2011. ,
The Unique Molecular Choreography of Giant Pore Formation by the Cholesterol-Dependent Cytolysins of Gram-Positive Bacteria, Annu Rev Microbiol, vol.69, pp.323-340, 2015. ,
Biogenesis and functions of bacterial S-layers, Nat Rev Microbiol, vol.12, pp.211-222, 2014. ,
Targeting Clostridium difficile Surface Components to Develop Immunotherapeutic Strategies Against Clostridium difficile Infection, Front Microbiol, vol.9, p.1009, 2018. ,
Characteristics and Immunological Roles of Surface Layer Proteins in Clostridium difficile, Ann Lab Med, vol.38, pp.189-195, 2018. ,
Taxonomic position of lecithinase-negative strains of Clostridium sordellii, J. Gen. Microbiol, vol.131, pp.1697-1703, 1985. ,
Neurotoxin gene clusters in Clostridium botulinum type A strains: sequence comparison and evolutionary implications, Cur. Microbiol, vol.46, pp.342-352, 2003. ,
Sequanix: a dynamic graphical interface for Snakemake workflows, Bioinformatics, vol.34, pp.1934-1936, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01874933
The Harvest suite for rapid core-genome alignment and visualization of thousands of intraspecific microbial genomes, Genome Biol, vol.15, p.524, 2014. ,
The RAST Server: rapid annotations using subsystems technology, BMC Genomics, vol.9, p.7, 2008. ,
Molecular Evolutionary Genetics Analysis version 6.0, Mol Biol Evol, vol.30, pp.2725-2729, 2013. ,
BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons, BMC Genomics, vol.12, p.402, 2011. ,
Proteinortho: detection of (co-)orthologs in large-scale analysis, BMC Bioinformatics, vol.12, p.124, 2011. ,
Clostridium tetani osteitis without tetanus, Emerg Infect Dis, vol.20, pp.1571-1573, 2014. ,