Infant botulism: Two case reports and electroneuromyogram findings

J. Bernardor (1) , J. Neveu (1) , H. Haas (1) , G. Pitelet (1) , M.-R. Popoff (2) , C. Mazuet (2) , E. Bérard (3) , C. Boulay (4) , B. Chabrol (4)

1 CHU-Lenval - Hôpitaux Pédiatriques de Nice Lenval
2 Bactéries anaérobies et Toxines
3 Hôpital l'Archet
4 Service Neuropédiatrie

Botulism is an uncommon severe neuromuscular disorder. We report two recent cases of confirmed infant botulism diagnosed in an 11-week and a 5-month-old infant along with electroneuromyogram (ENMG) findings. Then, we discuss the EMG features of infant botulism. In severe forms of infant botulism, presence of these features might help decide to use botulinum immune globulin. To our knowledge, case 1 is the first case reported in France based on confirmed dust contamination.

Mots clés: Botulinum toxin; Botulism; Electromyography; Infant

Domaines: Sciences du Vivant [q-bio]; Microbiologie et Parasitologie; Bactériologie; Biologie cellulaire; Organisation et fonctions cellulaires [q-bio.SC]; Interactions cellulaires [q-bio.CB]

J. Bernardor, J. Neveu, H. Haas, G. Pitelet, M.-R. Popoff, et al.. Infant botulism: Two case reports and electroneuromyogram findings. Archives de Pédiatrie, 2018, 25 (5), pp.340-343. ⟨10.1016/j.arcped.2018.05.002⟩. ⟨pasteur-02448645⟩