Antibody-mediated modulation of immune responses, Immunol Rev, vol.236, pp.265-75, 2010. ,
Fc? receptors as regulators of immune responses, Nat Rev Immunol, vol.8, pp.34-47, 2008. ,
Fc?RIIB in autoimmunity and infection: evolutionary and therapeutic implications, Nat Rev Immunol, vol.10, pp.328-371, 2010. ,
The regulation of lymphocyte activation by inhibitory receptors, Curr Opin Immunol, vol.16, pp.328-364, 2004. ,
Mouse and human FcR effector functions, Immunol Rev, vol.268, pp.25-51, 2015. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01281740
Type I and type II Fc receptors regulate innate and adaptive immunity, Nat Immunol, vol.15, pp.707-723, 2014. ,
Fc receptor-dependent mechanisms of monoclonal antibody therapy of cancer, Fc Receptors Current Topics in Microbiology and Immunology, vol.382, pp.373-92, 2014. ,
Increased natural killer cell expression of CD16, augmented binding and ADCC activity to rituximab among individuals expressing the Fc{gamma}RIIIa-158 V/V and V/F polymorphism, Blood, vol.110, pp.2561-2565, 2007. ,
Blood monocytes and their subsets: established features and open questions, Front Immunol, vol.6, p.423, 2015. ,
CD16 is indispensable for antibody-dependent cellular cytotoxicity by human monocytes, Sci Rep, vol.6, p.34310, 2016. ,
Activation of NK cell cytotoxicity, Mol Immunol, vol.42, pp.501-511, 2005. ,
Properties of mouse and human IgG receptors and their contribution to disease models, Blood, vol.119, pp.5640-5649, 2012. ,
Building better monoclonal antibody-based therapeutics, Nat Rev Cancer, vol.15, pp.361-70, 2015. ,
Specificity and affinity of human Fc? receptors and their polymorphic variants for human IgG subclasses, Blood, vol.113, pp.3716-3741, 2009. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00363931
Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma, J Clin Oncol Off J Am Soc Clin Oncol, vol.21, pp.3940-3947, 2003. ,
The FCGR3A polymorphism predicts the response to rituximab-based therapy in patients with non-Hodgkin lymphoma: a meta-analysis, Ann Hematol, vol.95, pp.1483-90, 2016. ,
Association of polymorphisms in FCGR2A and FCGR3A with degree of trastuzumab benefit in the adjuvant treatment of ERBB2/HER2-positive breast cancer: analysis of the NSABP B-31 trial, JAMA Oncol, vol.3, pp.335-376, 2017. ,
Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibodydependent cellular cytotoxic activity, Nat Biotechnol, vol.17, pp.176-80, 1999. ,
Engineered antibody Fc variants with enhanced effector function, Proc Natl Acad Sci, vol.103, pp.4005-4015, 2006. ,
Asymmetrical Fc engineering greatly enhances antibody-dependent cellular cytotoxicity (ADCC) effector function and stability of the modified antibodies, J Biol Chem, vol.289, pp.3571-90, 2014. ,
The current status and prospects of antibody engineering for therapeutic use: focus on glycoengineering technology, J Pharm Sci, vol.104, pp.930-971, 2015. ,
Obinutuzumab for the first-line treatment of follicular lymphoma, N Engl J Med, vol.377, pp.1331-1375, 2017. ,
Obinutuzumab-mediated high-affinity ligation of Fc?RIIIA/CD16 primes NK cells for IFN? production, Oncoimmunology, vol.6, p.1290037, 2017. ,
Rituximab-dependent cytotoxicity by natural killer cells influence of FCGR3A polymorphism on the concentration-effect relationship, Cancer Res, vol.64, pp.4664-4673, 2004. ,
Macrophages eliminate circulating tumor cells after monoclonal antibody therapy, J Clin Invest, vol.124, pp.812-835, 2014. ,
Macrophages contribute to the antitumor activity of the anti-CD30 antibody SGN-30, Blood, vol.110, pp.4370-4372, 2007. ,
Macrophages and Fc-receptor interactions contribute to the antitumour activities of the anti-CD40 antibody SGN-40, Br J Cancer, vol.100, pp.113-120, 2009. ,
Regulatory B cell production of IL-10 inhibits lymphoma depletion during CD20 immunotherapy in mice, J Clin Invest, vol.121, pp.4268-80, 2011. ,
Lymphoma depletion during CD20 immunotherapy in mice is mediated by macrophage FcgammaRI, FcgammaRIII, and FcgammaRIV, Blood, vol.112, pp.1205-1218, 2008. ,
STING activation reverses lymphoma-mediated resistance to antibody immunotherapy, Cancer Res, vol.77, pp.3619-3650, 2017. ,
Red pulp macrophages in the human spleen are a distinct cell population with a unique expression of Fc-? receptors, Blood Adv, vol.2, pp.941-53, 2018. ,
Macrophage activation and polarization, Front Biosci J Virtual Libr, vol.13, pp.453-61, 2008. ,
Glycoengineered CD20 antibody obinutuzumab activates neutrophils and mediates phagocytosis through CD16B more efficiently than rituximab, Blood, vol.122, pp.3482-91, 2013. ,
Glycoengineering of therapeutic antibodies enhances monocyte/macrophage-mediated phagocytosis and cytotoxicity, J Immunol, vol.192, pp.2252-60, 2014. ,
The function of Fc? receptors in dendritic cells and macrophages, Nat Rev Immunol, vol.14, pp.94-108, 2014. ,
Effective phagocytosis of low Her2 tumor cell lines with engineered, aglycosylated IgG displaying high Fc?RIIa affinity and selectivity, ACS Chem Biol, vol.8, pp.368-75, 2012. ,
Optimization of antibody binding to FcgammaRIIa enhances macrophage phagocytosis of tumor cells, Mol Cancer Ther, vol.7, pp.2517-2544, 2008. ,
Leukocyte composition of human breast cancer, Proc Natl Acad Sci, vol.109, pp.2796-801, 2012. ,
Aglycosylated IgG variants expressed in bacteria that selectively bind Fc?RI potentiate tumor cell killing by monocyte-dendritic cells, Proc Natl Acad Sci, vol.107, pp.604-613, 2010. ,
IgG Fc domains that bind C1q but not effector Fc? receptors delineate the importance of complement-mediated effector functions, Nat Immunol, vol.18, pp.889-98, 2017. ,
Recombinant antibody therapeutics: the impact of glycosylation on mechanisms of action, Trends Pharmacol Sci, vol.30, pp.356-62, 2009. ,
Aglycosylated immunoglobulin G1 variants productively engage activating Fc receptors, Proc Natl Acad Sci, vol.105, pp.20167-72, 2008. ,
Expression of full-length immunoglobulins in Escherichia coli: rapid and efficient production of aglycosylated antibodies, J Immunol Methods, vol.263, pp.133-180, 2002. ,
Revisiting the role of glycosylation in the structure of human IgG Fc, ACS Chem Biol, vol.7, pp.1596-602, 2012. ,
FcgammaRIV is a mouse IgE receptor that resembles macrophage FcepsilonRI in humans and promotes IgE-induced lung inflammation, J Clin Invest, vol.118, pp.3738-50, 2008. ,
URL : https://hal.archives-ouvertes.fr/pasteur-00363913
Genotyping single nucleotide polymorphisms (SNPs) and copy number variability (CNV) of the FCGRs (FCGR3A and FCGR2C) expressed on NK cells, Methods Mol Biol Clifton NJ, vol.1441, pp.43-56, 2016. ,
,
, RNase H-dependent PCR (rhPCR): improved specificity and single nucleotide polymorphism detection using blocked cleavable primers, BMC Biotechnol, 2011.
IgGA: a "cross-isotype" engineered human Fc antibody domain that displays both IgG-like and IgA-like effector functions, Chem Biol, vol.21, pp.1603-1612, 2014. ,
Immune complexes inhibit differentiation, maturation, and function of human monocyte-derived dendritic cells, J Immunol, vol.179, pp.673-81, 2007. ,
Use of an anti-CD16 antibody for in vivo depletion of natural killer cells in rhesus macaques, Immunology, vol.124, pp.215-237, 2008. ,
The binding epitopes of human CD16 (Fc gamma RIII) monoclonal antibodies. Implications for ligand binding, J Immunol, vol.157, pp.1576-81, 1996. ,
Impact of immune complex size and glycosylation on IgG binding to human Fc?Rs, J Immunol, vol.190, pp.4315-4338, 2013. ,
Contribution of human Fc?Rs to disease with evidence from human polymorphisms and transgenic animal studies, Front Immunol, vol.5, p.254, 2014. ,
Restricted processing of CD16a/Fc ? receptor IIIa N-glycans from primary human NK cells impacts structure and function, J Biol Chem, vol.293, pp.3477-89, 2018. ,
IgG Fc engineering to modulate antibody effector functions, Protein Cell, vol.9, pp.63-73, 2018. ,
Cell typespecific and site directed N-glycosylation pattern of Fc?RIIIa, J Proteome Res, vol.10, pp.3031-3040, 2011. ,
Identification of Fc gamma receptor glycoforms that produce differential binding kinetics for rituximab, Mol Cell Proteomics, vol.16, pp.1770-88, 2017. ,
Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets, Nat Med, vol.6, pp.443-449, 2000. ,
Fc gamma receptor IIb on GM-CSF macrophages controls immune complex mediated inhibition of inflammatory signals, PLoS ONE, vol.9, p.110966, 2014. ,
Inhibition of Fc?R-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and Fc?RIIb in human macrophages, Blood, vol.124, pp.3709-3727, 2014. ,
More than decoration: roles for natural killer group 2 member D ligand expression by immune cells, Front Immunol, vol.9, p.231, 2018. ,