Abstract : Preventing malaria infection through vaccination requires preventing every sporozoite inoculated by mosquito bite: a major challenge for Plasmodium falciparum. Plasmodium vivax sporozoites consist of tachysporozoites causing primary infection and bradysporozoites leading to relapses. We hypothesise that a candidate P. vivax vaccine with low efficacy against primary infection may substantially reduce transmission by preventing relapses.
https://hal-pasteur.archives-ouvertes.fr/pasteur-02425470 Contributor : Rogerio AminoConnect in order to contact the contributor Submitted on : Monday, December 30, 2019 - 3:35:38 PM Last modification on : Thursday, April 7, 2022 - 10:10:38 AM Long-term archiving on: : Tuesday, March 31, 2020 - 1:58:44 PM
Michael White, Rogerio Amino, Ivo Mueller. Theoretical Implications of a Pre-Erythrocytic Plasmodium vivax Vaccine for Preventing Relapses. Trends in Parasitology, Elsevier, 2017, 33 (4), pp.260-263. ⟨10.1016/j.pt.2016.12.011⟩. ⟨pasteur-02425470⟩