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The diagnosis of infectious diseases by whole genome next generation sequencing: a new era is opening

Abstract : As in other medical fields, the availability of next generation sequencing (NGS) techniques is about to revolutionize diagnostics of infectious diseases. The demonstration of the microbial origin of diseases and their diagnosis were initially based on the demonstration of the presence of a given pathogen in a given clinical sample, and was first dominated by culture assay for bacteria and later for viruses [...]
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Marc Lecuit, Marc Eloit. The diagnosis of infectious diseases by whole genome next generation sequencing: a new era is opening. Frontiers in Cellular and Infection Microbiology, Frontiers, 2014, 4, pp.25. ⟨10.3389/fcimb.2014.00025⟩. ⟨pasteur-02395735⟩

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