Writing -review & editing, C.Z. Funding This work was supported by the Agence Nationale de la Recherche (ANR 16 CE 16 0019 01 NEUROTUNN) and the EU Joint Programme on Neurodegenerative Diseases ,
is supported by Ph.D. fellowships from the China Scholarship Council (201306170046) and by an Institute Carnot fellowship, S.B. is supported by JPND-NeuTARGETs-ANR, 201602. ,
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