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Emergence of Disseminated Infections Due to Geosmithia argillacea in Patients with Chronic Granulomatous Disease Receiving Long-Term Azole Antifungal Prophylaxis

Abstract : We report two cases of invasive infections due to Geosmithia argillacea, an emerging mold, in patients with chronic granulomatous disease receiving prolonged azole antifungal prophylaxis. One patient died despite receiving a combination of four antifungals, and the other developed cerebral and medullary lesions under a combination of caspofungin, posaconazole, terbinafine, and gamma interferon.
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Submitted on : Friday, August 2, 2019 - 4:49:05 PM
Last modification on : Friday, March 27, 2020 - 2:38:14 AM

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Marie Machouart, Dea Garcia-Hermoso, Alexandre Rivier, Noura Hassouni, Emilie Catherinot, et al.. Emergence of Disseminated Infections Due to Geosmithia argillacea in Patients with Chronic Granulomatous Disease Receiving Long-Term Azole Antifungal Prophylaxis. Journal of Clinical Microbiology, American Society for Microbiology, 2011, 49 (4), pp.1681-1683. ⟨10.1128/JCM.02456-10⟩. ⟨pasteur-02262537⟩

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