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Miltefosine-based regimen as salvage therapy in Lomentospora prolificans bone and joint infection

Abstract : 1. Introduction We report the second case of miltefosine, terbinafine, and voriconazole-based regimen as salvage therapy in a Lomentospora prolificans bone and joint infection. A favorable outcome was observed when combined with aggressive surgery. A poor prior evolution was observed following three surgical procedures of debridement combined with terbinafine and voriconazole. This report of a safe and successful use of miltefosine highlights the need for an interdisciplinary expertise for appropriate surgical and medical treatment.
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https://hal-pasteur.archives-ouvertes.fr/pasteur-02193093
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Submitted on : Wednesday, July 24, 2019 - 11:33:46 AM
Last modification on : Friday, March 27, 2020 - 2:32:04 AM

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L. Quaesaet, E. Stindel, F. Lanternier, T. Williams, S. Jaffuel, et al.. Miltefosine-based regimen as salvage therapy in Lomentospora prolificans bone and joint infection. Médecine et Maladies Infectieuses, Elsevier Masson, 2018, 48 (1), pp.63-65. ⟨10.1016/j.medmal.2017.10.005⟩. ⟨pasteur-02193093⟩

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