, Biological diversity of prokaryotic type IV secretion systems, Microbiol Mol Biol Rev, vol.73, pp.775-808, 2009.
, The VirB5 protein localizes to the T-pilus tips in Agrobacterium tumefaciens, Microbiology, vol.153, pp.3766-3775, 2007.
, Identification of linked Legionella pneumophila genes essential for intracellular growth and evasion of the endocytic pathway, Infect Immun, vol.66, pp.950-958, 1998.
, Comparison of proteins involved in pilus synthesis and mating pair stabilization from the related plasmids F and R100-1: insights into the mechanism of conjugation, J Bacteriol, vol.181, pp.5149-5159, 1999.
, Plasticity of repetitive DNA sequences within a bacterial (Type IV) secretion system component, J Exp Med, vol.198, pp.1349-1360, 2003.
, F conjugation: back to the beginning, Plasmid, vol.70, pp.18-32, 2013.
, Modulation of the host innate immune and inflammatory response by translocated bacterial proteins, Cell Microbiol, vol.17, pp.785-795, 2015.
, VirE2, a type IV secretion substrate, interacts with the VirD4 transfer protein at cell poles of Agrobacterium tumefaciens, Mol Microbiol, vol.49, pp.1699-1713, 2003.
, Energetic components VirD4, VirB11 and VirB4 mediate early DNA transfer reactions required for bacterial type IV secretion, Mol Microbiol, vol.54, pp.1199-1211, 2004.
, Entry exclusion in F-like plasmids requires intact TraG in the donor that recognizes its cognate TraS in the recipient, Microbiology, vol.153, pp.442-451, 2007.
, Type IV secretion systems and their effectors in bacterial pathogenesis, Curr Opin Microbiol, vol.9, issue.2, pp.207-217, 2006.
, Type IV secretion and signal transduction of Helicobacter pylori CagA through interactions with host cell receptors; Toxins (Basel), 2017.
, Composition, structure and function of the Helicobacter pylori cag pathogenicity island encoded type IV secretion system, Future Microbiol, vol.10, issue.6, pp.955-965, 2015.
, Functional plasticity in the type IV secretion system of Helicobacter pylori, PLoS Pathog, vol.9, 2013.
, Characterization of a Coxiella burnetii ftsZ mutant generated by Himar1 transposon mutagenesis, J Bacteriol, vol.191, pp.1369-1381, 2009.
, Thirty-eight C-terminal amino acids of the coupling protein TraD of the F-like conjugative resistance plasmid R1 are required and sufficient to confer binding to the substrate selector protein TraM, J Bacteriol, vol.186, pp.6999-7006, 2004.
, Genetic complementation analysis of the Agrobacterium tumefaciens virB operon: virB2 through virB11 are essential virulence genes, J Bacteriol, vol.176, pp.3646-3660, 1994.
, Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila, Mol Microbiol, vol.7, pp.7-19, 1993.
, Altered intracellular targeting properties associated with mutations in the Legionella pneumophila dotA gene, Mol Microbiol, vol.14, pp.809-822, 1994.
, The expanding bacterial type IV secretion lexicon, Res Microbiol, vol.164, pp.620-639, 2013.
, Type VI secretion: a beginner's guide, Curr Opin Microbiol, vol.11, pp.3-8, 2008.
, Morphological and serological relationships of conjugative pili, Plasmid, vol.4, pp.155-169, 1980.
, Specification of surface mating systems among conjugative drug resistance plasmids in Escherichia coli K-12, J Bacteriol, vol.143, pp.1466-1470, 1980.
, The Legionella pneumophila icm locus: a set of genes required for intracellular multiplication in human macrophages, Mol Microbiol, vol.14, pp.797-808, 1994.
, Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires, Nat Genet, vol.48, pp.167-175, 2016.
, The DotL protein, a member of the TraG-coupling protein family, is essential for viability of Legionella pneumophila strain Lp02, J Bacteriol, vol.187, pp.2927-2938, 2005.
, Genetic evidence of a coupling role for the TraG protein family in bacterial conjugation, Mol Gen Genet, vol.254, pp.400-406, 1997.
, Towards an integrated model of bacterial conjugation, FEMS Microbiol Rev, vol.39, pp.81-95, 2014.
, The Coxiella burnetii Dot/Icm system delivers a unique repertoire of type IV effectors into host cells and is required for intracellular replication, PLoS Path, vol.7, 2011.
, The type VI secretion toolkit, EMBO Rep, vol.9, pp.735-741, 2008.
, The versatile bacterial type IV secretion systems, Nat Rev Microbiol, vol.1, pp.137-150, 2003.
, Definition of a bacterial type IV secretion pathway for a DNA substrate, Science, vol.304, pp.1170-1173, 2004.
, Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease, PLoS Genet, vol.6, issue.2, p.1000851, 2010.
, Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity, Nat Genet, vol.36, pp.1165-1173, 2004.
, Structural biology of bacterial type IV secretion systems, Annu Rev Biochem, vol.84, pp.603-629, 2015.
, Large-scale identification and translocation of type IV secretion substrates by Coxiella burnetii, Proc Natl Acad Sci U S A, vol.107, pp.21755-21760, 2010.
, Bacterial type IV secretion: conjugation systems adapted to deliver effector molecules to host cells, Trends Microbiol, vol.8, pp.354-360, 2000.
, Biogenesis, architecture, and function of bacterial type IV secretion systems, Annu Rev Microbiol, vol.59, pp.451-485, 2005.
, F-pili dynamics by live-cell imaging, Proc Natl Acad Sci U S A, vol.105, pp.17978-17981, 2008.
, Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth, Mol Microbiol, vol.38, pp.719-736, 2000.
, Cyclic RGD peptides interfere with binding of the Helicobacter pylori protein CagL to integrins alphaVbeta3 and alpha5beta1, Amino Acids, vol.43, issue.1, pp.219-232, 2012.
, Molecular evolution of Legionella pneumophila dotA gene, the contribution of natural environmental strains, Environ Microbiol, vol.12, pp.2711-2729, 2010.
, Evidence for acquisition of Legionella type IV secretion substrates via interdomain horizontal gene transfer, J Bacteriol, vol.187, pp.7716-7726, 2005.
, Functional dissection of the conjugative coupling protein TrwB, J Bacteriol, vol.192, pp.2655-2669, 2010.
, Infection-associated type IV secretion systems of Bartonella and their diverse roles in host cell interaction, Cell Microbiol, vol.10, pp.1591-1598, 2008.
, Helicobacter pylori chaperone-like protein CagT plays an essential role in the translocation of CagA into host cells, J Microbiol Biotechnol, vol.22, pp.1343-1349, 2012.
, The Legionella pneumophila IcmR protein exhibits chaperone activity for IcmQ by preventing its participation in high-molecular-weight complexes, Mol Microbiol, vol.40, pp.1113-1127, 2001.
, Discovery of virulence genes of Legionella pneumophila by using signature tagged mutagenesis in a guinea pig pneumonia model, Proc Natl Acad Sci U S A, vol.96, pp.8190-8195, 1999.
, Bartonella entry mechanisms into mammalian host cells, Cell Microbiol, vol.14, pp.1166-1173, 2012.
, Targeting of host organelles by pathogenic bacteria: a sophisticated subversion strategy, Nat Rev Microbiol, vol.14, pp.5-19, 2016.
URL : https://hal.archives-ouvertes.fr/pasteur-01326394
, IcmQ in the Type 4b secretion system contains an NAD+ binding domain, Structure, vol.21, pp.1361-1373, 2013.
, A specific genomic location within the icm/dot pathogenesis region of different Legionella species encodes functionally similar but nonhomologous virulence proteins, Infect Immun, vol.72, pp.4503-4511, 2004.
, Coevolution between nonhomologous but functionally similar proteins and their conserved partners in the Legionella pathogenesis system, Proc Natl
, Formation of a pathogen vacuole according to Legionella pneumophila: how to kill one bird with many stones, Cell Microbiol, vol.17, pp.935-950, 2015.
, Characterization of the F plasmid bifunctional conjugation gene, traG, Mol Gen Genet, vol.232, pp.145-153, 1992.
, Assembly and molecular mode of action of the Helicobacter pylori Cag type IV secretion apparatus, FEBS J, vol.278, pp.1203-1212, 2011.
, Molecular and structural analysis of the Helicobacter pylori cag type IV secretion system core complex, MBio, vol.7, pp.2001-02015, 2016.
, Structure of a type IV secretion system core complex, Science, vol.323, pp.266-268, 2009.
, Pilus assembly by Agrobacterium T-DNA transfer genes, Science, vol.273, pp.1107-1109, 1996.
, Why is entry exclusion an essential feature of conjugative plasmids?, Plasmid, vol.60, pp.1-18, 2008.
, In situ structure of the Legionella Dot/Icm type IV secretion system by electron cryotomography, EMBO Rep, vol.18, pp.726-732, 2017.
, An anomalous type IV secretion system in Rickettsia is evolutionarily conserved, PLoS ONE, vol.4, p.4833, 2009.
, Phylogenomics reveals a diverse Rickettsiales type IV secretion system, Infect Immun, vol.78, pp.1809-1823, 2010.
, Evidence of the presence of a functional Dot/Icm type IV-B secretion system in the fish bacterial pathogen Piscirickettsia salmonis, PLoS ONE, vol.8, 2013.
, Genome dynamics in Legionella: the basis of versatility and adaptation to intracellular replication; Cold Spring Harb Perspect Med, 2013.
, Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions, Front Microbiol, vol.2, 2011.
URL : https://hal.archives-ouvertes.fr/pasteur-01422820
, Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires' disease, Genome Biol, vol.15, p.505, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01329875
, The bacterial conjugation protein TrwB resembles ring helicases and F1-ATPase, Nature, vol.409, pp.637-641, 2001.
, Coupling factors in macromolecular type-IV secretion machineries, Curr Pharm Des, vol.10, pp.1551-1565, 2004.
, Use of chimeric type IV secretion systems to define contributions of outer membrane subassemblies for contact-dependent translocation, Mol Microbiol, vol.105, pp.273-293, 2017.
, Type IV secretion in gram-negative and grampositive bacteria, Mol Microbiol, 2018.
, Evolution of conjugation and type IV secretion systems, Mol Biol Evol, vol.30, pp.315-331, 2013.
URL : https://hal.archives-ouvertes.fr/pasteur-01374951
, Purification and characterization of the R64 shufflon-specific recombinase, J Bacteriol, vol.182, pp.2787-2792, 2000.
, Modulation of host cell function by Legionella pneumophila type IV effectors, Annu Rev Cell Dev Biol, vol.26, pp.261-283, 2010.
, Agrobacterium tumefaciens VirB6 protein participates in formation of VirB7 and VirB9 complexes required for type IV secretion, J Bacteriol, vol.185, pp.2867-2878, 2003.
, Agrobacterium tumefaciens VirB9, an outer-membrane-associated component of a type IV secretion system, regulates substrate selection and T-pilus biogenesis, J Bacteriol, vol.187, pp.3486-3495, 2005.
, Polar delivery of Legionella type IV secretion system substrates is essential for virulence, Proc Natl Acad Sci, vol.114, pp.8077-8082, 2017.
, Genes required for assembly of pili associated with the Helicobacter pylori cag type IV secretion system, Infect Immun, vol.82, pp.3457-3470, 2014.
, The mating pair stabilization protein, TraN, of the F plasmid is an outer-membrane protein with two regions that are important for its function in conjugation, Microbiology, vol.151, pp.3527-3540, 2005.
, Molecular evolution of the dotA gene in Legionella pneumophila, J Bacteriol, vol.185, pp.6269-6277, 2003.
, The transfer region of IncI1 plasmid R64: similarities between R64 tra and legionella icm/dot genes, Mol Microbiol, vol.35, pp.1348-1359, 2000.
, The Type IVB secretion system: an enigmatic chimera, Curr Opin Microbiol, vol.29, pp.22-29, 2015.
, Native structure of a type IV secretion system core complex essential for Legionella pathogenesis, Proc Natl Acad Sci U S A, vol.111, pp.11804-11809, 2014.
, Architecture of the type IV coupling protein complex of Legionella pneumophila, Nat Microbiol, vol.2, p.17114, 2017.
, Helicobacter exploits integrin for type IV secretion and kinase activation, Nature, vol.449, issue.7164, pp.862-866, 2007.
, In silico identification and characterization of putative Dot/Icm secreted virulence effectors in the fish pathogen Piscirickettsia salmonis, Microb Pathog, vol.92, pp.11-18, 2016.
, Right on Q: genetics begin to unravel Coxiella burnetii host cell interactions, Future Microbiol, vol.11, pp.919-939, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01999377
, F factor conjugation is a true type IV secretion system, FEMS Microbiol Lett, vol.224, pp.1-15, 2003.
, Type IV secretion system components as phylogenetic markers of entomopathogenic bacteria of the genus Rickettsiella, FEMS Microbiol Lett, vol.279, pp.167-173, 2008.
,
, Enterococcus faecalis PrgJ, a VirB4-like ATPase, mediates pCF10 conjugative transfer through substrate binding, J Bacteriol, vol.194, pp.404140-404151, 2012.
, Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal, Proc Natl Acad Sci U S A, vol.110, pp.707-715, 2013.
, The ins and outs of pertussis toxin, FEBS J, vol.278, issue.23, pp.4668-4682, 2011.
, Structure of a type IV secretion system, Nature, vol.508, pp.550-553, 2014.
, Mutations in the C-terminal region of TraM provide evidence for in vivo TraM-TraD interactions during F-plasmid conjugation, J Bacteriol, vol.187, pp.4767-4773, 2005.
, Structural basis of specific TraD-TraM recognition during F plasmid-mediated bacterial conjugation, Mol Microbiol, vol.70, pp.89-99, 2008.
, Multiple substrates of the Legionella pneumophila Dot/Icm system identified by interbacterial protein transfer, Proc Natl Acad Sci U S A, vol.101, pp.841-846, 2004.
, The origins of eukaryotic-like proteins in Legionella pneumophila, Int J Med Microbiol, vol.300, pp.470-481, 2010.
, Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages, Proc Natl Acad Sci U S A, vol.89, pp.9607-9611, 1992.
, Determinants of entry exclusion within Eex and TraG are cytoplasmic, J Bacteriol, vol.189, pp.6469-6473, 2007.
, Identification and subcellular localization of the Legionella pneumophila IcmX protein: a factor essential for establishment of a replicative organelle in eukaryotic host cells, Infect Immun, vol.68, pp.3971-3982, 2000.
, Phylogenetic analysis of Piscirickettsia salmonis by 16S, internal transcribed spacer (ITS) and 23S ribosomal DNA sequencing, Dis Aquat Organ, vol.35, pp.115-123, 1999.
, Predicted hexameric structure of the Agrobacterium VirB4 C terminus suggests VirB4 acts as a docking site during type IV secretion, Proc Natl Acad Sci U S A, vol.102, pp.1685-1690, 2005.
, Coxiella burnetii: turning hostility into a home, Cell Microbiol, vol.17, pp.621-631, 2015.
, Type IVB secretion systems of Legionella and other Gram-negative bacteria, Front Microbiol, vol.2, issue.136, 2011.
, The DotA protein from Legionella pneumophila is secreted by a novel process that requires the Dot/Icm transporter, EMBO J, vol.20, pp.5962-5970, 2001.
, A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes, Science, vol.295, pp.679-682, 2002.
, Crystal structure of Legionella DotD: insights into the relationship between type IVB and type II/III secretion systems, PLoS Pathog, vol.6, p.1001129, 2010.
, The Legionella IcmS-IcmW protein complex is important for Dot/Icm-mediated protein translocation, Mol Microbiol, vol.55, pp.912-926, 2005.
, Regulation of Helicobacter pylori virulence within the context of iron deficiency, J Infect Dis, vol.211, pp.1790-1794, 2015.
, Aggravating genetic interactions allow a solution to redundancy in a bacterial pathogen, Science, vol.338, pp.1440-1444, 2012.
, The physiology and biochemistry of pili, Adv Microb Physiol, vol.29, pp.53-114, 1988.
, The sexameric structure of a conjugative VirB4 protein ATPase provides new insights for a functional and phylogenetic relationship with DNA translocases, J Biol Chem, vol.287, pp.39925-39932, 2012.
, The Legionella pneumophila icmGCDJBF genes are required for killing of human macrophages, Infect Immun, vol.66, pp.2245-2255, 1998.
, Legionella and Coxiella effectors: strength in diversity and activity, Nat Rev Microbiol, vol.15, pp.591-605, 2017.
, The gonococcal genetic island and type IV secretion in the pathogenic Neisseria, Front Microbiol, vol.2, p.61, 2011.
, Genetic and functional characterization of the type IV secretion system in Wolbachia, J Bacteriol, vol.190, pp.5020-5030, 2008.
, Structure and function of interacting IcmR-IcmQ domains from a type IVb secretion system in Legionella pneumophila, Structure, vol.17, pp.590-601, 2009.
, Functional interactions of VirB11 traffic ATPases with VirB4 and VirD4 molecular motors in type IV secretion systems, J Bacteriol, vol.195, pp.4195-4201, 2013.
, A novel sheathed surface organelle of the Helicobacter pylori cag type IV secretion system, Mol Microbiol, vol.49, pp.219-234, 2003.
, Topology of Legionella pneumophila DotA: an inner membrane protein required for replication in macrophages, Infect Immun, vol.65, pp.571-578, 1997.
, Identification of Legionella pneumophila genes required for growth within and killing of human macrophages, Infect Immun, vol.61, pp.5361-5373, 1993.
, Role of Agrobacterium VirB11 ATPase in T-pilus assembly and substrate selection, J Bacteriol, vol.183, pp.5813-5825, 2001.
, Complete genome sequence of the incompatibility group I1 plasmid R64, Plasmid, vol.64, pp.92-103, 2010.
, The carboxyl terminus of protein TraD adds specificity and efficiency to F-plasmid conjugative transfer, J Bacteriol, vol.180, pp.6039-6042, 1998.
, VirB11 ATPases are dynamic hexameric assemblies: new insights into bacterial type IV secretion, EMBO J, vol.22, pp.1969-1980, 2003.
, The mating pair formation system of conjugative plasmids-a versatile secretion machinery for transfer of proteins and DNA, Plasmid, vol.54, pp.1-25, 2005.
, TraG-like proteins of DNA transfer systems and of the Helicobacter pylori type IV secretion system: inner membrane gate for exported substrates?, J Bacteriol, vol.184, pp.2767-2779, 2002.
, Legionella pneumophila utilizes the same genes to multiply within Acanthamoeba castellanii and human macrophages, Infect Immun, vol.67, pp.2117-2124, 1999.
, Possible origin of the Legionella pneumophila virulence genes and their relation to Coxiella burnetii, Mol Microbiol, vol.33, pp.669-667, 1999.
, Host cell killing and bacterial conjugation require overlapping sets of genes within a 22-kb region of the Legionella pneumophila genome, Proc Natl Acad Sci U S A, vol.95, pp.1669-1674, 1998.
, The Icm/Dot type-IV secretion systems of Legionella pneumophila and Coxiella burnetii, FEMS Microbiol Rev, vol.29, pp.65-81, 2005.
, Complete genome sequence of the Q-fever pathogen Coxiella burnetii, Proc Natl Acad Sci U S A, vol.100, pp.5455-5460, 2003.
, Type IVB secretion by intracellular pathogens, Traffic, vol.3, pp.178-185, 2002.
, Legionella pneumophila DotU and IcmF are required for stability of the Dot/Icm complex, Infect Immun, vol.72, pp.5983-5992, 2004.
, The Legionella pneumophila PilT homologue DotB exhibits ATPase activity that is critical for intracellular growth, J Bacteriol, vol.186, pp.1658-1666, 2004.
, Autophagy evasion and endoplasmic reticulum subversion: the yin and yang of Legionella intracellular infection, Annu Rev Microbiol, vol.70, pp.413-433, 2016.
, New insights into F-pilus structure, dynamics, and function, Integr Biol (Camb), vol.2, pp.25-31, 2010.
, A component of the Xanthomonadaceae type IV secretion system combines a VirB7 motif with a N0 domain found in outer membrane transport proteins, PLoS Pathog, vol.7, 2011.
, Bacterial killing via a type IV secretion system, Nat Commun, vol.6, p.6453, 2015.
, Composite system mediates twostep DNA uptake into Helicobacter pylori, Proc Natl Acad Sci, vol.107, pp.1184-1189, 2010.
,
, The Legionella IcmSW complex directly interacts with DotL to mediate translocation of adaptor-dependent substrates, PLoS Pathog, vol.8, 2012.
, Reassessing the role of DotF in the Legionella pneumophila type IV secretion system, PLoS ONE, vol.8, 2013.
, A unique basolateral type IV secretion model for the CagA oncoprotein of Helicobacter pylori, Cell Host Microbe, 2017.
, , p.5
, Architecture of the Helicobacter pylori Cag-type IV secretion system, FEBS J, vol.278, pp.1213-1222, 2011.
, Surface organelles assembled by secretion systems of Gramnegative bacteria: diversity in structure and function, FEMS Microbiol Rev, vol.36, pp.1046-1082, 2012.
, IcmF and DotU are required for optimal effector translocation and trafficking of the Legionella pneumophila vacuole, Infect Immun, vol.72, pp.5972-5982, 2004.
, The Legionella pneumophila IcmS-LvgA protein complex is important for Dot/ Icm-dependent intracellular growth, Mol Microbiol, vol.61, pp.596-613, 2006.
, Identification of the core transmembrane complex of the Legionella Dot/Icm type IV secretion system, Mol Microbiol, vol.62, pp.1278-1291, 2006.
, Identification of the DotL coupling protein subcomplex of the Legionella Dot/Icm type IV secretion system, Mol Microbiol, vol.85, pp.378-391, 2012.
, Cell biology of Legionella pneumophila, Curr Opin Microbiol, vol.2, pp.30-34, 1999.
, Conjugative transfer by the virulence system of Legionella pneumophila, Science, vol.279, pp.873-876, 1998.
, Bacterial type IV secretion systems: versatile virulence machines, Future Microbiol, vol.7, pp.241-257, 2012.
, Formation of a fibrous structure on the surface of Legionella pneumophila associated with exposure of DotH and DotO proteins after intracellular growth, Mol Microbiol, vol.39, pp.313-329, 2000.
, Legionella pneumophila is internalized by a macropinocytotic uptake pathway controlled by the Dot/Icm system and the mouse Lgn1. locus, J Exp Med, vol.194, pp.1081-1096, 2001.
, Identification of Coxiella burnetii type IV secretion substrates required for intracellular replication and Coxiella-containing vacuole formation, J Bacteriol, vol.195, pp.3914-3924, 2013.
, The all-alpha domains of coupling proteins from the Agrobacterium tumefaciens VirB/VirD4 and Enterococcus faecalis pCF10-Encoded type IV secretion systems confer specificity to binding of cognate DNA substrates, J Bacteriol, vol.197, pp.2335-2349, 2015.
, Chimeric coupling proteins mediate transfer of heterologous type IV effectors through the Escherichia coli pKM101-encoded conjugation machine, J Bacteriol, vol.198, pp.2701-2718, 2016.
, Structural insights into the roles of the IcmS-IcmW complex in the type IVb secretion system of Legionella pneumophila, Proc Natl Acad Sci, 2017.
, Additive effect on intracellular growth by Legionella pneumophila
, Icm/Dot proteins containing a lipobox motif, Infect Immun, vol.73, pp.7578-7587, 2005.
, Twelve pil genes are required for biogenesis of the R64 thin pilus, J Bacteriol, vol.181, pp.2038-2043, 1999.
, Coxiella burnetii express type IV secretion system proteins that function similarly to components of the Legionella pneumophila Dot/Icm system
, Mol Microbiol, vol.49, pp.965-976, 2003.
, Pore-forming activity is not sufficient for Legionella pneumophila phagosome trafficking and intracellular growth, Mol Microbiol, vol.32, pp.990-1001, 1999.
, Functional similarities between the icm/dot pathogenesis systems of Coxiella burnetii and Legionella pneumophila, Infect Immun, vol.71, pp.3714-3723, 2003.
, , p.25