Skip to Main content Skip to Navigation
Journal articles

Innate Lymphoid Cell Development: A T Cell Perspective

Abstract : Innate lymphoid cells (ILCs) and natural killer (NK) cells have garnered considerable interest due to their unique functional properties in immune defense and tissue homeostasis. Our current understanding of how these cells develop has been greatly facilitated by knowledge of T cell biology. Models of T cell differentiation provided the basis for a conceptual classification of these innate effectors and inspired a scheme of their activation and regulation. In this review, we discuss NK cell and ILC development from a "T cell standpoint" in an attempt to extend the analogy between adaptive T cells and their innate ILC and NK cell counterparts.
Document type :
Journal articles
Complete list of metadatas

Cited literature [161 references]  Display  Hide  Download

https://hal-pasteur.archives-ouvertes.fr/pasteur-02100997
Contributor : James Di Santo <>
Submitted on : Tuesday, May 7, 2019 - 2:49:41 PM
Last modification on : Friday, March 27, 2020 - 3:51:03 AM

File

Cherrier_2018_Immunity_post-pr...
Files produced by the author(s)

Identifiers

Citation

Dylan Cherrier, Nicolas Serafini, James Di Santo. Innate Lymphoid Cell Development: A T Cell Perspective. Immunity, Elsevier, 2018, 48 (6), pp.1091-1103. ⟨10.1016/j.immuni.2018.05.010⟩. ⟨pasteur-02100997⟩

Share

Metrics

Record views

361

Files downloads

929