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Viral Load Increases in SJL/J Mice Persistently Infected by Theiler's Virus after Inactivation of the 2m Gene

Stéphanie Aubagnac 1 Michel Brahic 1 Jean-François Bureau 1, *
* Corresponding author
Abstract : We show that inactivating the beta(2)m gene increases the viral load of SJL/J mice persistently infected by Theiler's virus. Together with previous results, this shows that the characteristics of Tmevp1, a locus which controls the amount of viral RNA that persists in the central nervous system, are those of an H-2 class I gene.
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Submitted on : Friday, April 12, 2019 - 9:29:02 AM
Last modification on : Monday, January 13, 2020 - 5:08:05 PM

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Stéphanie Aubagnac, Michel Brahic, Jean-François Bureau. Viral Load Increases in SJL/J Mice Persistently Infected by Theiler's Virus after Inactivation of the 2m Gene. Journal of Virology, American Society for Microbiology, 2001, 75 (16), pp.7723-7726. ⟨10.1128/JVI.75.16.7723-7726.2001⟩. ⟨pasteur-02097501⟩

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